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Deciphering IEC Necrosis-Triggered Colitis in FADDIEC-KO Mice

This study explores how RIP3- and CYLD-dependent necrosis of intestinal epithelial cells (IECs) leads to colitis in FADDIEC-KO mice. The research sheds light on the mechanisms underlying this process and its implications for inflammatory bowel disease.

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Deciphering IEC Necrosis-Triggered Colitis in FADDIEC-KO Mice

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  1. RIP3- and CYLD-dependent necrosis of IECs triggers colitis in FADDIEC-KO mice. P-S Welz et al. Nature000, 1-5 (2011) doi:10.1038/nature10273

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