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Ischemic Heart Disease

Ischemic Heart Disease

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Ischemic Heart Disease

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  1. Ischemic HeartDisease Alternative Names; Coronary Heart Disease (CAD) Arteriosclerotic Heart Disease (AHD) Jonas Vegsundvaag

  2. Epidemiology

  3. Ischemia occur when the oxygen and metabolic demands are not met Khouri, 1965

  4. Several Causes; Atherosclerosis Thrombosis Emboli

  5. Risk Factors • Age and Gender • Type of Diet (Esp. Saturated Fatty Acids) • Smoking • Previous Heart Attack and Strokes • Hereditary Risk Factors • Stress, Type A Personality • Temperature

  6. Left ventricle Right ventricle Mitral valve Tricuspidal valve Left atrium Right atrium

  7. Parasternal cross-section of the heart RV LV Normal situation Stimulated heart (dobutamin (β1)) ↑ inotropy, ↑ heart rate

  8. Dobutamin-stressecho, parasternal cross-section At rest Myocardial infaction area with scar Dilated left ventr. Ischemic stimulation: reduced contraction of viable myocardium and cavity dilatation Sub-ischemic stimulation: increased contrac- tion of viable myocardium and reduced cavity

  9. Pathophysiology; Clinical Consepts and Onset of Disease 6th Edition; Cardiovascular System Disorders; 466:470. • Price et Wilson • Department of Internal Medicine, Alesund Hospital, Alesund, Norway • http://www.heartstats.org/datapage.asp?id=5712 • http://www.healthline.com/adamcontent/coronary-heart-disease • http://www.ssb.no/