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Basal Ganglia

Basal Ganglia. Lec 13. Major Diseases of the Basal Ganglia. Parkinson’s disease Huntington’s disease Hemiballism Athetosis Dystonia Restless Leg Syndrome Psychiatric diseases (OCD ), Tourette’s syndrome. IT IS :Parkinson’s Disease. Motor Symptoms:-. The Cardinal signs of PD are :-

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Basal Ganglia

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  1. Basal Ganglia Lec13

  2. Major Diseases of the Basal Ganglia • Parkinson’s disease • Huntington’s disease • Hemiballism • Athetosis • Dystonia • Restless Leg Syndrome • Psychiatric diseases (OCD), Tourette’s syndrome

  3. IT IS :Parkinson’s Disease

  4. Motor Symptoms:- • The Cardinal signs of PD are :- 1- Tremor (Resting tremor). 2- Rigidity (muscle stiffness) 3- Brady Kinesia/ Akinesia. 4- Postural instability.

  5. Dauer W, Przedborski S.. Parkinson's disease: mechanisms and models. Neuron. 2003 39:889-909.

  6. Schapira AH, Olanow CW.. Neuroprotection in Parkinson disease: mysteries, myths, and misconceptions. JAMA. 2004 Jan 21;291(3):358-64.

  7. Deep Brain Stimulation (DBS) • DBS targets areas in the brain where uncontrolled movements originate. The targeted region is inactivated, not destroyed, by an implanted electrode. The electrode is connected via a wire running beneath the skin to a stimulator and battery pack in the patient's chest.

  8. Deep Brain Stimulation (DBS)

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