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Learn about the endocrine system, its glands, hormone production, regulation, and malfunctions. Explore key glands like the pituitary, thyroid, parathyroid, Islets of Langerhans, adrenal glands, and gonads. Understand the role of hormones in growth, metabolism, and reproduction.
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The Endocrine System Chapter 24A
The Endocrine System • Consists of the ductless glands of the body • Deposits hormones into the bloodstream • Helps control body functions
Hormones chemical messengers produced by the endocrine glands and transported in the bloodstream to other parts of the body
Hormones • Organic chemicals produced by the ES • Transported by blood • Specific • Secreted in small amounts
Hormones • Filtered by the kidneys and deactivated by the liver • Closely regulated • maintain homeostasis
Modes of Action • Steroid hormones diffuse through the cell membrane and bind to receptors. • Nonsteroid hormones combine with a membrane receptor and release chemicals into the cytoplasm.
Control of Hormone Secretions • Nervous system • Changes within the body • Negative feedback system
Malfunctions • Hyposecretion • underproduction of a hormone • Hypersecretion • overproduction of a hormone
The Endocrine Glands
Anterior Pituitary • Tropic hormones • stimulate growth and function of other endocrine glands
Anterior Pituitary • Growth hormone • height and size • regulates protein synthesis, breakdown of fats, formation of periosteum and epiphyseal plates
Abnormalities • Dwarfism • Giantism • Acromegaly
Posterior Pituitary • Stores and releases two hormones produced by the hypothalamus • oxytocin • antidiuretic
Thyroid Gland • Thyroxine • indirectly affects growth; stimulates heat production; increases oxygen use • disorders
Thyroid Gland • calcitonin • causes Ca+ to move from blood into bone tissue
Parathyroid Glands • parathyroid hormone • removes Ca+ from bone and into blood
Islets of Langerhans • Insulin • lowers blood sugar level • stimulates conversion of glucose to glycogen • Glucagon • raises blood sugar level
Islets of Langerhans • Disorders • hyperglycemia • hypoglycemia
Adrenal Glands • Adrenal cortex • Adrenal medulla • epinephrine • norepinephrine
Gonads and Sex Hormones • Gonads • reproductive organs • Male • androgens, e.g. testosterone • Female • estrogen and progesterone
Puberty Girls 12-13 years average Boys 14 years average
Secondary Sex Characteristics • body hair • body fat • muscle and bone growth • voice • skin • reproductive glands and organs change