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a. b. 1. 2. 3. 4. 5. 6. 7. 8. MW. KanaR. 21.6. Ori. Ip. ChlR. OC. 5.1. Lin. c. 4.4. 3.2. SC. 2.0. 1. Linear full sized excision product. 1.9. 1.7. Excision. 1.4. KanaR. 1.0. 2. Circularized full sized excision product. 0.8. 0.6. KanaR. d.

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0.6

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  1. a. b. 1 2 3 4 5 6 7 8 MW KanaR 21.6 Ori Ip ChlR OC 5.1 Lin c. 4.4 3.2 SC 2.0 1. Linear full sized excision product 1.9 1.7 Excision 1.4 KanaR 1.0 2. Circularized full sized excision product 0.8 0.6 KanaR d. 3. Circularized excision products by intra-molecular auto-reinsertion KanaR KanaR

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