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ESSENTIAL CONCEPTS OF METABOLISM

ESSENTIAL CONCEPTS OF METABOLISM. CHAPTER 5. Metabolism. Anabolism Catabolism. Energy Capture. Oxidation Reduction Redox. NAD + + e - -------> NADH. Oxidized form. Reduced form. Metabolic Lifestyles — Autotrophy. Photoautotroph Chemoautotroph.

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ESSENTIAL CONCEPTS OF METABOLISM

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  1. ESSENTIAL CONCEPTS OF METABOLISM CHAPTER 5

  2. Metabolism • Anabolism • Catabolism

  3. Energy Capture • Oxidation • Reduction • Redox NAD+ + e- -------> NADH Oxidized form Reduced form

  4. Metabolic Lifestyles — Autotrophy • Photoautotroph • Chemoautotroph

  5. Metabolic Lifestyles — Heterotrophy • Photoheterotroph • Chemoheterotroph

  6. Metabolic Lifestyles Summary

  7. Enzymes • Role • Structure

  8. Enzyme Sites • Active Site

  9. Enzyme Inhibition • Competitive

  10. Enzyme Inhibition • Non-competitive

  11. Allosteric Site

  12. Temperature Reaction Rate Influences

  13. pH Reaction Rate Influences

  14. Enzyme concentration Reactant concentration Product concentration Enzyme Reaction Rates

  15. LeChatlier’s Principle and the BioChemical Pathway A + B C + D Want to go forward? Increase concentration of A + B or Decrease concentration of C + D

  16. Anaerobic metabolism • Glycolysis

  17. Anaerobic Pathways • Alternatives • Fermentation

  18. Emden-Meyerhoff Standard glycolysis

  19. Entner-Douderoff pathway

  20. Aerobic Metabolism • Krebs Cycle (aka. TCA cycle, citric acid cycle)

  21. Krebs cycle

  22. Electron Transport Chain

  23. Electron Transport Chain

  24. Chemiosmosis

  25. Anaerobic Respiration • Final electron acceptor differences

  26. Fat Catabolism • Glycerol • Fatty Acids

  27. Protein Catabolism • Deamination • Carbon skeleton usage

  28. Protein anabolism(amino acid synthesis) Precursors off of Krebs cycle

  29. Photosynthesis

  30. Photosynthesis

  31. Photosynthesis

  32. Other Metabolic Processes • Photoheterotrophy (Rhodopseudomonas) • Light as energy carbohydrates as carbon source • Chemoautotrophy (Nitrobacter) HNO2 as energy CO2 as carbon source

  33. Uses Of Energy • Biosynthesis • Membrane Transport Active transport/antiport • Movement ATP to drive flagella or cilia

  34. Bioluminescence • Microbial Source

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