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Chemistry 501 Handout 10 Lipids Chapter 10

Dep. of Chemistry & Biochemistry Prof. Indig. Chemistry 501 Handout 10 Lipids Chapter 10. Lehninger. Principles of Biochemistry. by Nelson and Cox, 5 th Edition; W.H. Freeman and Company. Two conventions for naming fatty acids. Fatty Acids. Stearic acid. Oleic acid.

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Chemistry 501 Handout 10 Lipids Chapter 10

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  1. Dep. of Chemistry & Biochemistry Prof. Indig Chemistry 501 Handout 10LipidsChapter 10 Lehninger. Principles of Biochemistry. by Nelson and Cox, 5th Edition; W.H. Freeman and Company

  2. Two conventions for naming fatty acids.

  3. Fatty Acids Stearic acid Oleic acid

  4. The packing of fatty acids into stable aggregates

  5. Glycerol and a triacylglycerol

  6. Triacylglycerols provide stored energy and insulation Fatty stores in cells Guinea pig adipocytes Cotyledon cell from a seed of Arabidopsis

  7. Many foods contain triacylglycerols Fatty acid composition of three food fats

  8. Waxes serve as energy stores and water repellents Triacontanoylpalmitate The major component of beeswax

  9. Some common types of storage and membrane lipids

  10. Glycerophospholipids The backbone of phospholipids

  11. Some phospholipids have ether-linked fatty acids

  12. Galactolipids and sulfolipids Three glycolipids of chloroplast membranes

  13. Archaebacteria contain unique membrane lipids

  14. Sphingolipids are derivatives of sphingosine

  15. Sphingolipids at cell surfaces are sites of biological recognition Glycosphingolipids as determinants of blood groups

  16. Phospholipids and sphingolipids are degraded in lysosomes The specificities of phospholipases

  17. Inherited human diseases resulting from abnormal accumulations of membrane lipids Abnormal ganglioside deposits in lysosomes (brain cell) Tay-Sachs

  18. Sterols have four fused carbon rings Cholesterol

  19. Arachidonic acid and some eicosanoid derivatives

  20. Steroids derived from cholesterol

  21. Vitamin D3 production and metabolism a hormone that regulates Ca+2 uptake in the intestines and calcium levels in kidney and bones Rickets

  22. Gene SLC24A5 Two variants Difference: just one amino acid

  23. Vitamin A1 and its precursor and derivatives Isoprene structural unit

  24. fibrinogen fibrin Some other biologically active isoprenoid compounds involved in the formation of active prothrombin

  25. inhibits the formation of active prothrombin Wisconsin Alumni Research Foundation +arin

  26. Lipids as pigments in plants and bird feathers

  27. Working with Lipids

  28. Determination of the structure of a fatty acid by mass spectrometry

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