Electrophilic Aromatic Substitution: Nitration of Aromatic Compounds and Product Distribution

Feb 12, 2026

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Lecture 11b explores the nitration of aromatic systems as a significant example of electrophilic aromatic substitution (EAS). It discusses the theoretical expectations of product distribution from a mono-substituted arene, predicting 40% ortho, 40% meta, and 20% para products. The lecture delves into the factors that influence these distributions, including the electronic effects of substituents, steric hindrance, and actual experimental data that may differ from statistical predictions. Understanding these principles is crucial in organic chemistry synthesis and reactivity.

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Electrophilic Aromatic Substitution: Nitration of Aromatic Compounds and Product Distribution

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