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Blood Typing. ABO. Discovery Education streaming - Asset Details Go to Discovery Education Click on Video Segment (6:02). ABO Blood Group. Three alleles A, B, O or I A , I B , i Phenotypes of Blood types: A B AB O. NOTE: A and B are codominant.
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Blood Typing ABO
Discovery Education streaming - Asset Details • Go to Discovery Education • Click on Video Segment (6:02)
ABO Blood Group • Three alleles A, B, O • or IA, IB, i • Phenotypes of Blood types: • A • B • AB • O NOTE: A and B are codominant
Drop of Blood Red blood cells have antigens Plasma has antibodies Don’t mix same letter antigens with antibodies
Antigens on RBC antigens antibodies
Antigens on surface Rh A
Agglutination (clumping)Animation: Cytotoxic (Type II Hypersensitivity)
Blood Typing Simulation • A sera is colored blue • B sera is colored yellow • Rh sera is colorless
ABO Blood Type • ABO Blood Typing
Type A + A Rh B
Type B Pos A Rh B
Type AB+ A Rh B
Type O neg. A Rh B
Rh+ and Rh- dominant Rh positive gene (+) produces the Rh antigen recessive Rh negative gene (-) does not produce an antigen
Rh+/Rh+ Rh+/Rh- Rh+ Rh-/Rh- = Rh-
(DD) or (Dd) = Rh+ (dd) = Rh- (they do not have the key Rh antigens).
Rh + or - ? Anti-Rh antibodies .
Best Blood • If you include the Rh factor, then the universal donor becomes O Negative while the universal recipient becomes AB Positive.
Percentages in U.S. • O Positive 38.4% • A Positive 32.3% • B Positive 09.4% • O Negative 07.7% • A Negative 06.5% • AB Positive 03.2% • B Negative 01.7% • AB Negative 00.7%