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BASIC AND CLINICAL RESEARCH LINKS

This overview by Dr. Romulo S. de Villa, an expert in Molecular and Nutritional Oncology, highlights the integral connection between basic and clinical research in medicine. It emphasizes the importance of understanding disease processes and developing innovative diagnostic tools and treatments. By utilizing advanced laboratory techniques and epidemiological analysis, researchers aim to improve patient outcomes through accurate testing, effective treatment strategies, and minimizing disease risks. This comprehensive approach fosters a better understanding of disease mechanisms at molecular, cellular, and tissue levels.

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BASIC AND CLINICAL RESEARCH LINKS

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  1. BASIC AND CLINICAL RESEARCH LINKS Romulo S. de Villa, MD, PhD Molecular & Nutritional Oncologist Professor of Biochemistry & Nutrition, FEU-NRMF Molecular Biology & Biotechnology Consultant

  2. Overview of Medical Research (Basic & Clinical) • A Scientific Investigation to • understand the disease process • develop new and improve existing • diagnostic tools • (clinical testing for validity, accuracy & precision) • treatment (prophylactic & therapeutic) • (clinical testing for ) • Understand the disease process by observing • patient (clinical & community) • tissue laboratory • cellular laboratory • molecular laboratory

  3. Basic science will develop: tools of diagnosis agents for treatment Clinical medicine will test: tools of diagnosis agents for treatment Understand Disease Mechanism

  4. Understanding the Disease Process • Epidemiologic identification of causative agent or factor and • Critical analysis of clinical course • Biochemical and Physiologic Mechanisms of the disease at the following levels: • tissue • cellular • molecular

  5. Developing and ImprovingDiagnostic Tools • Developing laboratory procedures • detect the difference in a sick individual • indicated by results of • biochemical and physiologic investigation of disease mechanism • Improving laboratory procedures • utilize new more sensitive, more specific technologies • (Clinical Testing: to determine accuracy)

  6. Developing and ImprovingTreatment • Developing agents and procedures that: • reduce the risk of developing the disease • modify or affect biochemical and physiologic mechanisms of the disease that will: • diminish clinical manifestations • prevent recurrence • reduce risk of death from the disease • (Clinical/Community Trial: to determine effectiveness)

  7. Thank You !

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