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TGF-beta induces Wnt10b in osteoclasts from female mice to enhance coupling to osteoblasts

TGF-beta induces Wnt10b in osteoclasts from female mice to enhance coupling to osteoblasts. Osteoscoop - Issue N°325 – February 2013. Preosteoblasts. +. Wnt10b. BMP6. Osteoblasts. Bone mineralization. Osteoclasts. S1P. Bone formation. Bone resorption. Preosteoblasts. +. Wnt10b.

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TGF-beta induces Wnt10b in osteoclasts from female mice to enhance coupling to osteoblasts

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  1. TGF-beta induces Wnt10b in osteoclasts from female mice to enhance coupling to osteoblasts Osteoscoop - Issue N°325 – February 2013

  2. Preosteoblasts + Wnt10b BMP6 Osteoblasts Bonemineralization Osteoclasts S1P Bone formation Bone resorption

  3. Preosteoblasts + Wnt10b BMP6 Osteoblasts Bonemineralization Osteoclasts S1P Bone formation Bone resorption + Smad TGF-b1 2 3 Bone resorption

  4. Preosteoblasts + Wnt10b BMP6 Osteoblasts Bonemineralization Osteoclasts S1P Bone formation Bone resorption Wnt10b + Smad TGF-b1 2 3 Bone resorption

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