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Discovering the Molecular Anatomy Project: An Integrated View of Human Digestion

The Molecular Anatomy Project (MAP) provides an integrated approach to understanding biological systems, particularly the human digestive system. Designed for general users, educators, students, and researchers, it offers a wealth of resources including detailed anatomical and physiological views of digestion, narrative descriptions of organ functions, and insights into the molecules involved in digestion such as enzymes and hormones. By comparing similar molecules and linking to structural biology resources, MAP serves as a vital gateway for learning about the intricate processes of digestion and related diseases.

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Discovering the Molecular Anatomy Project: An Integrated View of Human Digestion

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  1. Exploring the MAP web-site Shuchismita Dutta March 2006

  2. The Molecular Anatomy Project • What is it? • Integrated view of a biological system • Who is it for? • General users, educators, students and researchers. • How does it work? • Select an organ system to explore • Read narrative version of how it functions • Browse through brief accounts of the molecules that participate in the functioning (enzyme, hormone etc.) • Why is it important? • Provides integrated view • Comparison of molecules with similar sources and/or functions • Gateway into PDB for users not familiar with structural biology or with the specific organ system

  3. The human digestive system • Where: Anatomical view of digestion • organ system, organ, cell • How: Physiological view of digestion • membrane potentials, muscle contractions in peristalsis • hormone control, feedback control • What: Biochemical view of digestion • digestion of proteins, carbohydrates, lipids by enzymes, cofactors • What if: Common diseases • Online Mendelian Inheritance in Man (OMIM) • Integrated molecular view of digestion in MAP

  4. Where does it happen? Organ System Cells Organ http://cwx.prenhall.com/bookbind/pubbooks/silverthorn2/medialib/Image_Bank/html/custom20.html

  5. How does it happen? Membrane Potential Muscle contraction http://cwx.prenhall.com/bookbind/pubbooks/silverthorn2/medialib/Image_Bank/html/custom20.html

  6. What happens in digestion? Digestion of protein Digestion of carbohydrates http://cwx.prenhall.com/bookbind/pubbooks/silverthorn2/medialib/Image_Bank/html/custom20.html

  7. What if? Search for diseases related to stomach

  8. Content Management System (CMS) Author 2 Author 3 Author 1 WWW Author 4 http://www.steptwo.com.au/papers/kmc_evaluate/

  9. The MAP and mapdev sites • http://map.rutgers.edu/ • http://mapdev.rutgers.edu/

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