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ProKnee Professional Protection

ProKnee aims to tackle the 100,000 - 200,000 ACL ruptures occurring annually by introducing a groundbreaking wearable device designed for athletes. With 60,000 - 75,000 ACL reconstructions performed each year since surgery costs exceed $10,000 and rehabilitation takes about a year, our solution focuses on general risk assessment for prevention. Utilizing mechanical and physiological modeling, the device features integrated sensors to monitor knee movement and muscle activation. Our business model includes phases for prototyping, FDA approvals, and market release to sports teams.

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ProKnee Professional Protection

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  1. ProKneeProfessional Protection Ravi Chacko CEO Chase McCaleb CFO Walker Plash CMO Perry Yin CTO George Zhou CRO

  2. Problem | Market | Company | Product| Business Plan | Development| Finances ACL Injury • 100,000 -200,000 rupturs per year1 • 60,000-75,000 ACL reconstructions are performed annually2 • Surgery > $10,000; Rehab >$10,000; Time ~ 1 year 3 • Lifelong effects (i.e. Patellofemoral Syndrome, Osteoarthritis) • No currently available options for general risk assessment aimed towards prevention 1. Mayo Clinic Online 2. JD Hubbell, MD; E Schwartz, MD; http://emedicine.medscape.com/article/89442-overview 3. WebMD

  3. Problem | Market | Company | Product| Business Plan | Development| Finances Market • CDC estimates 7.2mil high school athletes in the US1 • NCAA comprises 400,000+ athletes • 700+ men’s and 500+ women’s soccer teams total • FIFA estimates 265mil people play soccer worldwide2 • In soccer, 70% of all ACL injuries are non-contact3 • UEFA’s top 25 teams have an operating income of over $1 billion and revenue of $7 billion in 20094 CDC: MMWR; September 29, 2006 / 55(38);1037-1040; http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5538a1.htm A Junge; J Dvorak; Br J Sports Med 2007 41: i3-i7; doi: 10.1136/bjsm.2007.036020 Katharina Grimm, MD; Holly Silver, PT; Bert Mandelbaum, MD; Health and Fitness for the Female Football Player ; http://www.fifa.com/mm/document/afdeveloping/medical/ffb_gesamt_e_20035.pdf http://www.forbes.com/lists/2009/34/soccer-values-09_Soccer-Team-Valuations_Rank.html

  4. Problem | Market | Company | Product| Business Plan | Development| Finances Mechanical and Physiological Modeling Wearable during athletic movements Massive database Small scale data collection Mechanical or Physiological Modeling Laboratory based movements The ProKnee Advantage

  5. Problem | Market | Company | Product| Business Plan | Development| Finances Design

  6. Problem | Market | Company | Product| Business Plan | Development| Finances Design – Insole Attachment • Gyroscope/Accelerometer • Work together to give position to calculate ankle angle • Wire • Connects to knee straps for power and to relay data • Force Sensors • Force summed to find moment at knee at impact • Determines time • of impact

  7. Problem | Market | Company | Product| Business Plan | Development| Finances Design – Knee Straps • Gyroscope/Accelerometer • Work together to give position to calculate flexion angle and medial motion angle • EMG (VL-ST) • Measures muscle activation • Wire • Connects to hip pack for power electronics and relay data

  8. Problem | Market | Company | Product| Business Plan | Development| Finances Design – Hip Pack • Battery (9V) • Power electronics in unit • USB Memory (1 GB) • Stores data for use with software later • Gyroscope/Accelerometer • Work together to give position and angle of torso • Wire • Connects to knee straps to power electronics and receive information

  9. Problem | Market | Company | Product| Business Plan | Development| Finances Design

  10. Problem | Market | Company | Product| Business Plan | Development| Finances Business Model

  11. Problem | Market | Company | Product| Business Plan | Development| Finances Business Model (cont.)

  12. Problem | Market | Company | Product| Business Plan | Development| Finances Phase I Phase II Phase III Phase IV Months: 0 6 18 30 • Phase I • Prototype 1 – Accurately model knee movement: • Test 1: Differentiate between people • Test 2: Differentiate between motions of an individual • Prototype 2 – Portable enough for athletic use • Maintain accuracy and repeatability • Display movements and muscle firing in a computer model

  13. Problem | Market | Company | Product| Business Plan | Development| Finances Phase I Phase II Phase III Phase IV Months: 0 6 18 30 • Phase II • Apply for FDA approval and patent • License to industry and academia • Clinical Trials 1 (Predictive) • Phase III • Clinical Trials 2 (Preventative) • Market to sports teams • 1st generation release • Phase IV • Review data for 2nd generation release

  14. Problem | Market | Company | Product| Business Plan | Development| Finances Phase I Budget

  15. Problem | Market | Company | Product| Business Plan | Development| Finances Financial Projections Phase I Phase II Phase III Phase IV

  16. Thank you • Dr. Paul Sadja • Associate Professor of Biomedical Engineering • Jim Gossett • Associate Athletics Director for Sports Medicine • Paige Plash • Physical Therapist, COO Encore Rehabilitation • Dr. Elizabeth Hillman • Assistant Professor of Biomedical Engineering • Keith Yeager • Senior Staff Associate, Laboratory Manager

  17. Questions?

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