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Conversion of wedge - dash to Fischer projection

Conversion of wedge - dash to Fischer projection. The concepts deals with the conversion of the wedge dash representation of a given molecule in a Fischer projection.

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Conversion of wedge - dash to Fischer projection

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  1. Conversion of wedge - dash to Fischer projection The concepts deals with the conversion of the wedge dash representation of a given molecule in a Fischer projection With the help of this animation user will be easily able to convert any molecule given in wedge dash representation to planer Fischer projection , hence will be able to study the stereochemistry of the given molecule By Rachit Agarwal Department of chemistry IIT Bombay

  2. Master layout Beginner’s level Bond coming out of the plane wedge With two carbon center (red dots) advance level Bond on the plane With three carbon center (red dots) dash Wedge – dash representation Here bond of C-R2 , C-R3 are in the plane , while of C-R1 is out of the plane and C-R4 inside the plane, the bond C-R4 is exactly behind the bond C-R1, but to show the C-R4 bond it is shown sideways Bond going in the plane T While looking the molecule from top or bottom the plane which is considered is of thickness T. In which the top layer passes through 2 carbon center and the lower layer through 1 carbon center Carbon center R1 R2 R3 and R4 are general notation for the atom

  3. Definition and rules for the users Molecule with 2 chiral center Molecule with 3 chiral center There are certain rules that are to be followed while making the Fischer projection Rule no 1) User should view the molecule from the same place while making the projection i.e. top right, top left, bottom right, bottom left Rule no 2) In Fischer projection the atoms/bonds which are in the horizontal line should come out of the plane while those are in vertical line should be going inside the plane Rule no 3) While rotating the bonds about any atom (chiral) the stereochemistry of the molecule does not changes

  4. Analogy / Scenario / Action / Example 3-D view of the molecule from a different angle so as to show all the atoms wedge – dash representation of the given molecule 3-D view of the given wedge dash molecule The first 3-D molecule is rotated about the bond joining red and black atoms , such that orange atom comes out of the plane, green goes inside the plane and blue comes on the plane and the corresponding wedge – dash on the right side

  5. The heading over the slides (for user to understand) There are total 8 types of option to be followed each containing of three (3) steps The hierarch is shown below

  6. Step 1 Actual slide to be displayed Select the level Option 1 Option 2 For beginners Molecule with two carbon atom For advance Molecule with three carbon atom

  7. Step 2A Actual slide to be displayed (option 1 selected) Select the view point bottom right bottom left Top left Top right Option 1

  8. Step 3AA Actual slide to be displayed (top left view in option 1 selected) Top left view Top left view Initial display of the page final display of the page Instruction on next slides

  9. Step 3AA

  10. Step 3AB Actual slide to be displayed (bottom left view in option 1 selected) Bottom left view bottom left view Initial display of the page final display of the page Instruction on next slides

  11. Step 3AB

  12. Step 3AC Actual slide to be displayed (top right view in option 1 selected) Top right view Top right view Initial display of the page final display of the page Instruction on next slides

  13. Step 3AC

  14. Step 3AD Actual slide to be displayed (bottom right view in option 1 selected) bottom right view Bottom right view Initial display of the page final display of the page Instruction on next slides

  15. Step 3AD

  16. Step 2B Actual slide to be displayed (option 2 selected) Select the view point bottom right bottom left Top left Top right Option 2

  17. Step 3BA Actual slide to be displayed (top left view in option 2 selected) Top left view Top left view Top left view Initial display of the page final display of the page Intermediate step Continued on the next page ….

  18. Step 3BA Instruction on next slide

  19. Step 3BA

  20. Step 3BB Actual slide to be displayed (bottom left view in option 2 selected) Bottom left view bottom left view bottom left view Initial display of the page final display of the page Intermediate step Continued on the next page ….

  21. Step 3BB Instruction on next slides

  22. Step 3BB

  23. Step 3BC Actual slide to be displayed (top right view in option 2 selected) Top right view Top right view Top right view Initial display of the page final display of the page Intermediate step Continued on the next page ….

  24. Step 3BC Instruction on next slides

  25. Step 3BC

  26. Step 3BD Actual slide to be displayed (bottom right view in option 2 selected) bottom right view Bottom right view Top right view Initial display of the page final display of the page Intermediate step Continued on the next page ….

  27. Step 3BD Instruction on next slides

  28. Step 3BD

  29. Links for further studies

  30. Questionnaire Draw the Fischer of the following molecules A B C

  31. Answers A B C

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