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Understanding Force-Frequency Relationship in Cardiac Function: An Analysis of Flat-Biphasic Abnormality

Explore the intricate relationship between heart rate and cardiac contractility with a focus on flat-biphasic abnormalities. This study delves into the impacts of varying heart rates on stroke volume and systolic blood pressure, shedding light on the dynamics of cardiac function. Discover the implications of different Force-Frequency profiles and their effects on cardiovascular performance.

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Understanding Force-Frequency Relationship in Cardiac Function: An Analysis of Flat-Biphasic Abnormality

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  1. Force-Frequency Relationship (flat-biphasic abnormal) HF = 60 bmp ESV = 120 ml SBP = 110 mmHg SBP/ESV = 0.9 HF = 80 bmp ESV = 100 ml SBP = 120 mmHg SBP/ESV = 1.2 HF = 100 bmp ESV = 81 ml SBP = 130 mmHg SBP/ESV = 1.6 HF = 120 bmp ESV = 95 ml SBP = 140 mmHg SBP/ESV = 1.5 2 1.5 1 Delta SP/ESV (peak – rest) = 1.5 - 0.9 = 0.6

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