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Cellular Membranes. I . General Functions. A. Compartmentalization. B. Selective Barrier. Figure 6.8. C. Responder to External Signals. Figure 11.6. D. Intra. or Extracellular Interactions. Figure 6.26. Figure 6.30. E. Biochemical Activities. Figure 11.10. F. Energy Transformation.
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Cellular Membranes I. General Functions A. Compartmentalization B. Selective Barrier Figure 6.8 C. Responder to External Signals Figure 11.6
D. Intra. or Extracellular Interactions Figure 6.26 Figure 6.30 E. Biochemical Activities Figure 11.10
F. Energy Transformation G. Transporter
A. Gorter & Grendel 1925 II. History B. Davson & Danielli 1935 C. Singer & Nicholson 1972 G & G 1920’s
III. Structural Molecules A. Lipids 2. Cholesterols 1. Phospholipids Figure 3.9A Figure 3.9C Figure 4.6
B. Carbohydrates 1. Oligosaccharides Sialic acid Sialic acid Figure 4.6 Figure 5.1 2. Antigens and Labeling
C. Proteins 1. Integral a. Domains
2. Peripheral Figure 5.1 3. Lipid Anchored Inositol
A. Issues IV. Fluidity 1. Temperature Figure 4.6
2. Interactions Figure 5.1
V. Mechanisms for Movement A. Passive Transport 1. Requirements b. Molecular size a. Favorable and with concentration gradient c. Slight molecular or atomic polarity 2. Mechanisms c. Facilitated Diffusion a. Simple Diffusion b. Osmosis
Figure 5.3A & B Figure 5.4 Figure 4.6 Figure 5.5 Figure 5.6
B. Active Processes 1. Requirements a. Needs Energy b. Against concentration gradient c. Protein channel or involves many proteins 2. Mechanisms a. Molecular b. Bulk = i. Endocytosis vs. ii. Exocytosis c. Bulk = Cell-mediated
Figure 5.8 Figure 5.9 Figure 4.6 Figure 5.9 Figure 5.9