1. Complex assembly of well-defined block copolymers Karen L. Wooley (Washington University) and Darrin J. Pochan (University of Delaware),DMR-0210247 Supramolecular (self) assembly of well-defined macromolecules in solution is a powerful method by which to produce interesting and discrete nanoscale objects. A common limitation with self assembly processes is the types of morphologies that can be accessed. In 2004, we identified a new toroidal structure, within the phase diagram of ABC triblock copolymers of acrylic acid, methyl acrylate and styrene, PAA-b-PMA-b-PS. In 2005, the block copolymer composition, molecular weight and topology were found to be critical parameters to allow for the formation of the toroidal assemblies. Additionally, studies to probe the nature and stoichiometry of a counterion (diamine) and the solution solvent/non-solvent composition have identified a new disc morphology. 1. THF + • Addition of diamine • Addition to THF/H2O soln to 0.1 wt% Amphiphilic ABC triblock copolymers of PAA-b-PMA-b-PS assemble into unique discs (cryo-TEM) and toroids (TEM image with uranyl acetate stain), and the conditions have been optimized under which each is obtained (upper and middle). In contrast, AB or AC diblock copolymers or ACB triblock copolymers failed to produce these morphologies (lower). J. Am. Chem. Soc., 2005, 127(24), 8592-8593; Langmuir, 2005, 21(16), 7533-7539; Science 2004, 306, 94-97

2. NIRT: One-, two-, and three-dimensional superstructured materials from well-defined, complex nanoscale components, DMR-0210247Craig J. Hawker (U.C.-Santa Barbara), Tomasz Kowalewski (Carnegie Mellon University), Michael E. Mackay (Michigan State University), Darrin J. Pochan (University of Delaware), Jill D. Pasteris, Jacob Schaefer, Karen L. Wooley (Washington University) Education Under this grant, four students have completed their Ph.D. dissertations, seven graduate students are pursuing their Ph.D. degrees. Two undergraduate students and three postdoctoral research associates have also been supported. • Outreach • Faculty and student members of this team have conducted many visits to grade schools in the cities of Lansing, MI, Pittsburgh, PA and Saint Louis, MO. • Second grade school students were also hosted for a visit to chemistry laboratories at Washington University in Saint Louis. • More than 20 peer-reviewed publications have been published to disseminate the results from this research and provide an educational tool for the students involved. • Each Ph.D. student involved in this NIRT has given at least two oral presentations at external scientific conferences. Michael Mackay with David Germack and Brooke Van Horn (Ph.D. students from K. L. Wooley’s laboratory) taught 5th grade students concepts of atomic force microscopy by having the students operate like an AFM.