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Pain Stimulator

Pain Stimulator. Adam Platt Jen Wells Biz Slyziuk Kalee McFadden Bryan Eckerle February 16, 2004. Dr. Stephen Bruehl. Research Interests Endogenous Pain Regulatory Systems, Psychobiology of Emotions

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Pain Stimulator

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  1. Pain Stimulator Adam Platt Jen Wells Biz Slyziuk Kalee McFadden Bryan Eckerle February 16, 2004

  2. Dr. Stephen Bruehl • Research Interests • Endogenous Pain Regulatory Systems, Psychobiology of Emotions • Focus: Understanding endogenous pain regulatory systems and dysfunction associated with chronic pain. • Interaction between cardiovascular and pain regulatory systems to maintain homeostasis during painful stimuli compared to interaction in chronic pain patients

  3. Methods • Vibration • Electrical Stimulus • Thermal Stimulus • Pressure Stimulus

  4. Importance • Stimulation of C-fibers • 12m/s • Use of placebo vs. response with drugs • Measures level of activity of receptors • Draw conclusions on natural pain systems in humans

  5. Drugs to be Tested • Naloxone • Blocks opiate receptors • Used clinically for heroine overdose • Injected into patient • Yohimbine • Blocks 2 adrenergic receptors which inhibit release of norepinephrine • Used clinically for erectile dysfunction (orally) • For Dr. Bruehl’s purposes, the FDA has only approved injections

  6. Problems with Existing Device • No electronic output • Oral reading • No accurate measurement of pressure • Lever system with constant weight • No adjustability for height or hand dominance • Adjustable only for finger placement

  7. Our Design • Device • Maintain lever system • Most stable design • Reposition weight to be placed vertically above finger • Contact Point • Between top two joints on index finger of dominant hand • Middle Phalanx #2

  8. Our Design… Cont. • Table • Transportation • Positioning • Adjustable Height • Sliding Tracks • Forearm length • Slider scale mounted to table displaying “No Pain” to “Worst Pain Imaginable”

  9. Materials • Aluminum • Lucite • Steel

  10. Device Construction • In process • Featheringill machine shop

  11. Device with Measurements

  12. LabView • Timer • Sliding Scale • Digital Display • Graphical Output • Audiovisuals • Digital Data Storage • Patient • Administrator • Date • Experimental Data

  13. Schematic Slider Scale Device (Pressure Transducer) PC Computer LabVIEW A/D Converter

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