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Tuberculosis Research Funding

Tuberculosis Research Funding. Erin S. Dante H. Background. One third of the world’s population is infected with TB . - In 2012, nearly 9 million people around the world became sick with TB disease. -There were around 1.3 million TB-related deaths worldwide . Background.

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Tuberculosis Research Funding

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  1. Tuberculosis Research Funding Erin S. Dante H.

  2. Background • One third of the world’s population is infected with TB. -In 2012, nearly 9 million people around the world became sick with TB disease. -There were around 1.3 million TB-related deaths worldwide.

  3. Background • TB is a leading killer of people who are HIV infected. • A total of 9,945 TB cases (a rate of 3.2 cases per 100,000 persons) were reported in the United States in 2012.

  4. Claims • Research and funding are needed in order to find effective ways to implement new tools and approaches in resource-limited environments, this includes clinical and operations research, program and policy design, and monitoring and evaluation. • Funding should focus on approaches to screening, diagnosing, case-finding, and curing TB to stop the spread of disease and development of better drugs.

  5. Budget Timeline

  6. Tuberculosis Impact Year 2015 2.5 Billion Dollars: • will be used to conduct global research on impact of Tuberculosis • Who the disease infects • Ages most vulnerable to the disease • Men v Women • Children vs Elderly • Ethnic Groups • Countries/Regions

  7. Medication and Prevention Year 2020 2.5 Billion Dollars : • will be used on drug developments and vaccines to prevent and cure Tuberculosis. • Host Doctoral Scientist and Pharmaceutical Companies to collaborate on drug developments. • Focused education in targeted underprivileged areas.

  8. Trials Year 2025 2.5 Million Dollars: • will be used on Clinical Trials • Will include human volunteers • About 7,000 participants nation wide • Studies will cover a span of 5 years

  9. Distribution Year 2030 2.5 Million Dollars: • Dollars will be used on Mass Drug Production and Distribution • Shipping • Packaging • Marketing

  10. Evidence • The challenge is even greater than it was in the 1940s and 50s when most of the current TB drugs were discovered because • the bar for safety is much higher now; and • drugs need to be compatible with those used for treating HIV/TB co-infections.

  11. Evidence • Finding new drugs for any disease is a long and expensive process. • funding for neglected diseases in general and TB drug discovery specifically remains miserably inadequateas compared to research and funding for anti-wrinkle, baldness, and cosmetic surgeries.

  12. Concerns • Some patients may still have the disease even after clinical trials • Budgeting could become inadequate because of economy and inflation progressing over the next 20 years

  13. Resources • http://www.cdc.gov/tb/topic/globaltb/default.htm • http://www.stoptb.org/global/research/areas.asp • http://www.fda.gov/drugs/developmentapprovalprocess/conductingclinicaltrials/default.htm

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