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Impact of Anti-miR-130b Antagomirs on Cell Death in MM.1Re Cells Treated with Dexamethasone

This study explores the effects of anti-miR-130b antagomirs on cell death in MM.1Re cells. MM.1Re cells were transfected with either control or anti-miR-130b antagomirs (10 nM) for 24 hours. Following transfection, the cells were treated with various concentrations of dexamethasone alongside MM.1S cells for an additional 48 hours. Cell death was assessed using Annexin V staining, providing insights into the potential therapeutic strategies for multiple myeloma through modulation of miRNA levels.

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Impact of Anti-miR-130b Antagomirs on Cell Death in MM.1Re Cells Treated with Dexamethasone

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  1. S3. MM.1Re cells transfected with control or anti-miR-130b antagomirs (10nM) for 24hrs, then subsequently treated with a range of dex concentrations along side MM.1S cells for an additional 48hrs are stained with Annexin V to measure cell death.

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