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Update on PED Research

Update on PED Research. Lisa Becton, DVM, MS, DACVPM Dir. Swine Health Information & Research National Pork Board . Current Status of PED . PED continues to be a major health challenge for U.S. producers into 2014

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Update on PED Research

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  1. Update on PED Research Lisa Becton, DVM, MS, DACVPM Dir. Swine Health Information & Research National Pork Board

  2. Current Status of PED • PED continues to be a major health challenge for U.S. producers into 2014 • Since it was first diagnosed in May of 2013, there have been a total of 2962 cases reported: • CASE reports are different than SITE reports. • IA = 1095; OK = 290; NC = 367; MN = 396; KS = 171 • Data can be found at www.aasv.org

  3. PED case #’s/month (as of Jan 31st , 2013)

  4. National Pork Board Focus • Research focus - New virus therefore needed research on PEDv and impact for US producers • Development and communication of producer information/resources • Containment/management strategies • Work with USDA/stakeholders and develop next steps for emerging disease response • Other needs?

  5. PED Research Efforts

  6. Development of Research Priorities • *Swine Health Committee – producers, veterinarians, advisors (university, government, industry) • PED Strategic Task Force • Input from AASV and NPPC membership • State Pork Association input

  7. PEDv Research Priorities Initial Research Priorities: • Basic understanding of the characteristics and pathogenesis of PEDv and development of standard samples for use • Development and validation of diagnostic testing for antigen and antibody detection for PEDv and for oral fluids • Environmental stability of the virus on various surfaces and substrates and effectiveness of sanitation efforts • Epidemiology of the disease

  8. Funded PEDv Research – June 2013 • Hesse, KSU:13-228 Tissue localization, shedding, virus carriage, antibody response and aerosol transmission of Porcine Epidemic Diarrhea virus (PEDV) following inoculation of feeder pigs • Wang, OSU: 13-222 Propagation of PEDV in tissue culture and development of standardized reference samples for use in diagnostic testing • Collins, UMN:13-238 Development and validation of isolation and diagnostic testing detection for PEDv • Collins, UMN:13-239 Development and validation of diagnostic testing for antigen and antibody detection for PEDV • Yoon, ISU:13-226 Oral fluid testing for cost-effective and efficient surveillance and control of porcine epidemic diarrhea virus in swine populations

  9. Funded PEDv Research (continued) • Morrison, UMN: 13-216 Epidemiologic investigation on propensity for lateral spread of PED virus • Goyal, UMN:13-215 Environmental Stability of PEDV (Porcine Epidemic Diarrhea virus) • Holtkamp, ISU: 13-227 Evaluation of time and temperature sufficient to kill PEDV in swine feces on metal surfaces • Holtkamp, ISU: 13-248 Evaluation of the efficacy of Stalosan®F for inactivating porcine epidemic diarrhea virus (PEDv) and PRRS in swine feces on the surface of trailers used to haul live pigs

  10. PEDv Research for Fall 2013 • RFP was posted at www.pork.org/Research • Proposals submitted to NPB • Sow immunity proposals selected by the Committee • Remaining proposals that meet the call priorities will be reviewed Feb 19-20th, 2014

  11. Funded Research for Sow Immunity - 2013 • Giménez-Lirola, ISU: 13-264 Defining PEDV maternal humoral immunity and correlates of neonatal protection • Clement, SDSU: 13-263 Duration and level of PEDV neutralizing antibodies for clinical protection using feedback protocols • Murtaugh, UMN: 13-262 PEDV feedback protocol optimization to improve immunity and productivity Since June 2013, the Board has approved >$1,000,000 for PED

  12. Additional PED project funded 2013-2014 • Pillatzki, ISU: 13-266 Feed transmission of PEDV to neonatal pigs • Bowman, OSU: 14-150 Bioassay for Porcine Epidemic Diarrhea Virus contaminated feed Since June 2013, the Board has approved >$1,000,000 for PED Funding for 2014 - TBD

  13. PEDv Research Focus for 2014 • Committee discussion Feb 19-20th on continuing needs for PED research, to include: • Further investigation of feed stuffs as vehicle for infection • Development of a rapid/pen-side test for feed • Assess capabilities for whole genome sequencing from current sample types • Cooperation, communication and collaboration are key to address this ongoing issue!

  14. PED Research • Information and updates on funded projects available at www.pork.org/PED

  15. Thank you! • lbecton@pork.org • 515-223-2791

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