Deep Brain Stimulation: Brain Pacemakers
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Deep Brain Stimulation: Brain Pacemakers. Kaitlin Abbate. What is Deep Brain Stimulation (DBS)?. Surgical treatment involving placement of brain pacemaker into the brain Sends electrical impulses to various places in the brain
Deep Brain Stimulation: Brain Pacemakers
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Deep Brain Stimulation:Brain Pacemakers Kaitlin Abbate
What is Deep Brain Stimulation (DBS)? • Surgical treatment involving placement of brain pacemaker into the brain • Sends electrical impulses to various places in the brain • Changes the brain activity that was previously happening so it becomes more normal
Components of the Pacemaker • Implanted Pulse generator (IPG) • Encased in titanium • Sends impulses to area of brain to interfere with neural activity • Generally placed near clavicle • Extension • Connects leads to IPG • Runs from head, down neck, behind ear, and to IPG in chest • Leads • Coiled wire insulated in polyurethane with four platinum electrodes • Lead to the specific targeted site of brain
What does it treat? • Many movement disorders • Tremor • Dystonia • Parkinson’s disease • Tourette syndrome • Also, affective disorders • Major Depression • Chronic pain • However, it is not anywhere near 100% effective yet for any of the above disorders
For Parkinson’s Disease • Tremor, rigidity, postural instability • Controls symptoms so medication is not needed anymore • Mostly targets subthalamic nucleus and globus pallidus inerna • parts of brain where tremors generally occur • Pacemaker intended to stop tremor before it begins and control the brain activity
Major Depression • No evidence to support the idea that DBS helps depression • However, there was a study with 6 patients • Implanted electrodes into frontal cortex of brain • When current turned on, 4 out of 6 patients reported “black cloud lifting” and were more alert • Patients were previously resistant to meds and psychotherapy
Complications/Side Effects • Most common side effects (may only be temporary): • Apathy • Hallucinations • Compulsive gambling • Hypersexuality • Brain shifts during surgery • Potential for electrodes to be displaced • Can lead to personality changes
So, is it worth it? • Well, no one is really sure that pacemaker actually works • Placebo Effect possibly • Very different from heart pacemaker • Heart pacemaker either works or doesn’t • Brain is more complex in the way that it is more prone to a lot of change especially with age • In conclusion, there is a lot of controversy • Mostly ethical reasons
Sources • "Brain Pacemaker at AllExperts." Expert Archive Questions. Web. 25 Apr. 2010. <http://en.allexperts.com/e/b/br/brain_pacemaker.htm>. • "Deep Brain Stimulation." Wikipedia, the Free Encyclopedia. Web. 25 Apr. 2010. <http://en.wikipedia.org/wiki/Deep_brain_stimulation>. • Stein, Rob. "The Potential of 'Brain Pacemakers'" Washington Post (2004). Print.