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This chapter explores the four basic types of tissues in the human body: epithelial, connective, muscular, and nervous. Epithelial tissue is characterized by closely packed cells forming sheets that cover surfaces and line cavities, featuring distinct apical surfaces and a basement membrane. It is avascular but innervated, showing significant regenerative capacity. The chapter categorizes epithelial tissue into simple and stratified types, detailing cell shapes. Additionally, it delves into connective tissue's diverse structures, functions, and types, emphasizing the extracellular matrix's role in tissue classification.
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Tissues Chapter 4
Tissues • groups of cells with common role • 4 basic types: • Epithelial • Connective • Muscular • Nervous
Epithelial Tissue • Cells close together – continuous sheets • Cover surfaces & line cavities- always a free surface =Apical surface • Basement membrane of connective tissue • No blood vessels- avascular • Have a nerve supply • High capacity for cell division.
Categories- Table 4.1 • Simple epithelium = • 1 layer of cells • Stratified Epithelium= • more than 1 layer of cells • Cell Shapes = • squamous, cuboidal, columnar, transitional (change shape)
Simple Epithelium • Squamous= single layer of flat cells. • Important for filtration (kidneys) or diffusion (lungs & capillaries) • Called endothelium when lining heart, blood and lymphatic vessels • Called mesothelium when in serous membranes
Pseudostratified Columnar appears stratified: nuclei at various levels
Pseudostratified Columnar appears stratified: nuclei at various levels
Stratified Squamous Epithelium • Apical layer cells are flat • Deep layers vary from cuboidal to columnar • Cells in the basal layer divide and move upward toward apical surface • Found in areas of surface wear & tear
Transitional Epitheliumvariable in appearance—cells can stretch
Transitional Epitheliumvariable in appearance—cells can stretch
Connective Tissue • Most abundant tissue type • small cells far apart • large amount of extracellular material (matrix) • Often good blood supply • Found between other tissues • Classified using matrix characteristics
Connective Tissue Cellsvary with tissue type • Fibroblasts- present in several tissues • secrete fibers & ground substance • Macrophages- from monocytes • Engulf bacteria & cell debris by phagocytosis • Plasma cells- develop from B lymphocytes • Make antibodies
Connective Tissue Cells • Mast cells- near blood cells • part of reaction to injury- histamine • Adipocytes= fat cells or adipose cells • Store triglycerides (fat)
Extracellular Matrix • Fluid, gel or solid plus protein fibers • Ground substance-between cells and fibers • Fibers- 3 types • Collagen fibers: very strong & flexible • Elastic fibers: smaller stretch and return to original length • Reticular fibers: provide support & strength • found in basement membranes & organ support
Loose Connective Tissue • Areolar • Adipose • Reticular
Classification • Dense Connective tissue • Dense regular • Dense irregular • Elastic
Cartilage • Dense network of collagen & elastic fibers embedded in chondroitin sulfate • stronger than dense fibrous • Cells = chondrocytes • Occur singly or in groups • Found in spaces called lacunae • Surrounded by perichondrium • No blood vessels or nerves
Classification - Cartilage • 3 types • Hyaline- fibers not easily visible • Fibrocartilage- fibers visible • Strongest type. E.g. in vertebral discs • Elastic- chondrocytes in threadlike network e.g. ear cartilage