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THE AUSTRALIA AND NEW ZEALAND CARDIOTHORACIC ORGAN TRANSPLANT REGISTRY

THE AUSTRALIA AND NEW ZEALAND CARDIOTHORACIC ORGAN TRANSPLANT REGISTRY. SEVENTEENTH ANNUAL REPORT 1984 – 2012. ANZCOTR 2012. NUMBER OF ALL TRANSPLANTS BY YEAR 1984 - 2012. ANZCOTR 2012. NUMBER OF ALL TRANSPLANTS* 1984 - 2012. ANZCOTR 2012. *Includes domino, heterotopic and retransplants.

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THE AUSTRALIA AND NEW ZEALAND CARDIOTHORACIC ORGAN TRANSPLANT REGISTRY

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  1. THE AUSTRALIA AND NEW ZEALAND CARDIOTHORACIC ORGAN TRANSPLANT REGISTRY SEVENTEENTH ANNUAL REPORT 1984 – 2012 ANZCOTR 2012

  2. NUMBER OF ALL TRANSPLANTS BY YEAR 1984 - 2012 ANZCOTR 2012

  3. NUMBER OF ALL TRANSPLANTS* 1984 - 2012 ANZCOTR 2012 *Includes domino, heterotopic and retransplants

  4. ALL HEART TRANSPLANTS BY HOSPITAL 1984 - 2012 ANZCOTR 2012

  5. HEART LUNG TRANSPLANTS BY HOSPITAL 1986 - 2012 Prince Charles 2005 figure includes one retransplant ANZCOTR 2012

  6. SINGLE LUNG TRANSPLANTS BY HOSPITAL 1990 - 2012 ANZCOTR 2012

  7. BILATERAL LUNG TRANSPLANTS BY HOSPITAL 1992 - 2012 Includes retransplants ANZCOTR 2012

  8. COMBINED WAITING LIST ACTIVITY 2012 ANZCOTR 2012 *Contains complete calendar year activity from all Registry Participant Centres. nb lungs column includes heart/lung procedures

  9. PRE TRANSPLANT DIAGNOSISHEART 1984 - 2012 Other 13% ISCHAEMIC HEART DISEASE 36% Peripartum CM 1% Familial CM 2% Congenital HD 6% Viral CM / Myocarditis 3% Retransplant 1% IDIOPATHIC DILATED CARDIOMYOPATHY 40% ANZCOTR 2012

  10. PRE TRANSPLANT DIAGNOSIS 1984 - 2012 n = 2298 ANZCOTR 2012

  11. PRE-TRANSPLANT STATUS HEARTS 1996 -2012 ANZCOTR 2012

  12. PRE-TRANSPLANT STATUS HEARTS 1993 - 2012 ANZCOTR 2012

  13. DONOR / RECIPIENT STATE OF ORIGIN HEARTS 1984 - 2012 Number ANZCOTR 2012

  14. DONOR / RECIPIENT STATE OF ORIGIN HEARTS 1984 - 2012 ANZCOTR 2012

  15. Mean Waiting Time to TransplantHEARTS 1984 - 2012 DAYS YEAR ANZCOTR 2012

  16. WAITING DAYS TO HEART TRANSPLANT 1984-2012 Due to limitations in the software, values over 1000 , until 2012, are represented as 999) ANZCOTR 2012

  17. Mean Recipient Age at TransplantHEARTS 1984 -2012 Age(yrs) Year ANZCOTR 2012

  18. RECIPIENT AGE AT HEART TRANSPLANT YEARS 1984 - 2012 ANZCOTR 2012

  19. Hearts Mean Donor Age 1984 - 2012 Age in years Year ANZCOTR 2012

  20. DONOR AGE HEARTS - YEARS 1984-2012 ANZCOTR 2012

  21. HEARTS - Mean Ischaemic Time 1984 - 2012 Minutes Year ANZCOTR 2012

  22. MEAN HEART ISCHAEMIC TIME - MINUTES1984-2012 ANZCOTR 2012

  23. ACTUARIAL SURVIVAL - HEART TRANSPLANT 1984 - 2012 n* = Number alive at start of year ANZCOTR 2012

  24. ACTUARIAL SURVIVAL - HEART TRANSPLANT 1984 - 2012 Percent Survival YEAR Survival by Cutler-Ederer life tables, comparisons by log rank Cox-Mantel ANZCOTR 2012

  25. ACTUARIAL SURVIVAL – ORTHOTOPIC v HETEROTOPIC v DOMINO TRANSPLANTS 1984 - 2012 ANZCOTR 2012

  26. Actuarial Survival Orthotopic Hearts v Heterotopic Hearts 1984 - 2012 Percent Survival Survival by Cutler-Ederer life tables, comparisons by log rank Cox-Mantel ANZCOTR 2012

  27. ACTUARIAL SURVIVAL ALL HEARTS PERIOD COMPARISON 1984 – 2012 p<0.001 Percent Survival Survival by Cutler-Ederer life tables, comparisons by log rank Cox-Mantel ANZCOTR 2012

  28. ACTUARIAL SURVIVAL HEARTS PERIOD COMPARISON 1984 - 2012 ANZCOTR 2012 *N = NUMBER ALIVE AT START OF YEAR

  29. ACTUARIAL SURVIVAL PRE TRANSPLANT DIAGNOSIS 1984 - 2012 IDCM v IHD p<0.005 IHD v Others p<0.005 Percent Survival by Cutler-Ederer life tables, comparisons by log rank Cox-Mantel ANZCOTR 2012

  30. ACTUARIAL SURVIVAL PRE TRANSPLANT DIAGNOSIS HEARTS 1984 – 2012 ANZCOTR 2012

  31. ACTUARIAL SURVIVAL PRE-TRANSPLANT STATUS HEARTS 1984 - 2012 p=ns Percent Survival by Cutler-Ederer life tables, comparisons by log rank Cox-Mantel ANZCOTR 2012

  32. ACTUARIAL SURVIVAL PRE-TRANSPLANT STATUS HEARTS 1984 - 2012 ANZCOTR 2012

  33. ACTUARIAL SURVIVAL RECIPIENT AGE BY GENDER HEARTS 1984 - 2012 ANZCOTR 2012 *N= NUMBER ALIVE AT START OF YEAR

  34. ACTUARIAL SURVIVAL BY RECIPIENT AGE AND GENDER HEARTS 1984 - 2012 Percent Survival MALES 0-39 yrsv MALES>39yrs p<0.005 MALES>39yrs v FEMALES>39yrs p <0.05 ANZCOTR 2012 Survival by Cutler-Ederer life tables, comparisons by log rank Cox-Mantel

  35. ACTUARIAL SURVIVAL DONOR AGE HEARTS 1984 - 2012 * ANZCOTR 2012 * 2 OF THE 16 CASES IN THE GREATER THAN 59 YEARS CATEGORY ARE HETEROTOPIC HEART TRANSPLANTS

  36. ACTUARIAL SURVIVAL DONOR AGE HEARTS 1984 - 2012 0-16yrs v 40-49yrs p<0.001 0-16yrs v 50-59yrs p<0.005 17-39yrs v 40-49yrs p<0.001 17-39yrs v 50-59yrs p<0.009 Percent Survival YEAR 2 OF THE 11 CASES IN THE GREATER THAN 59 YEARS CATEGORY ARE HETEROTOPIC HEART TRANSPLANTS Survival by Cutler-Ederer life tables, comparisons by log rank Cox-Mantel ANZCOTR 2012

  37. ACTUARIAL SURVIVAL DONOR GENDER HEARTS 1984 - 2012 ANZCOTR 2012

  38. ACTUARIAL SURVIVAL DONOR GENDER HEARTS 1984 - 2012 p=ns Percent Survival Year Survival by Cutler-Ederer life tables, comparisons by log rank Cox-Mantel ANZCOTR 2012

  39. ACTUARIAL SURVIVAL RECIPIENT GENDER HEARTS 1984 - 2012 ANZCOTR 2012

  40. ACTUARIAL SURVIVAL RECIPIENT GENDER HEARTS 1984 - 2012 Percent Survival p=ns Year Survival by Cutler-Ederer life tables, comparisons by log rank Cox-Mantel ANZCOTR 2012

  41. ACTUARIAL SURVIVAL ISCHAEMIC TIME HEARTS 1984 - 2012 ANZCOTR 2012

  42. ACTUARIAL SURVIVAL ISCHAEMIC TIME HEARTS 1984 - 2012 p=ns Survival by Cutler-Ederer life tables, comparisons by log rank Cox-Mantel ANZCOTR 2012

  43. ACTUARIAL SURVIVAL CROSSMATCH HEARTS 1984 - 2012 ANZCOTR 2012

  44. ACTUARIAL SURVIVAL CROSSMATCH HEARTS 1984 - 2012 p < 0.01 Percent Survival Year Survival by Cutler-Ederer life tables, comparisons by log rank Cox-Mantel ANZCOTR 2012

  45. ACTUARIAL SURVIVAL PEAK PANEL REACTIVE ANTIBODIES ALL HEARTS 1984 - 2012 ANZCOTR 2012

  46. ACTUARIAL SURVIVAL PEAK PRA ALL HEARTS 1984 - 2012 p=ns Percent Survival Year ANZCOTR 2012 Survival by Cutler-Ederer life tables, comparisons by log rank Cox-Mantel

  47. ACTUARIAL SURVIVAL CMV STATUS HEARTS 1984 - 2012 ANZCOTR 2012

  48. ACTUARIAL SURVIVAL CMV STATUS HEARTS 1984 - 2012 p=ns Percent Survival Year R+ve = R+veD+ve or R+veD-ve Survival by Cutler-Ederer life tables, comparisons by log rank Cox-Mantel ANZCOTR 2012

  49. ACTUARIAL SURVIVAL HLA MISMATCH HEARTS 1984 - 2012 ANZCOTR 2012

  50. ACTUARIAL SURVIVAL HLA MISMATCH HEARTS 1984 - 2012 p<0.05 Percent Survival Year ANZCOTR 2012 Survival by Cutler-Ederer life tables, comparisons by log rank Cox-Mantel

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