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EGFR-L858R-T790M

A. 1. 2. 3. 4. EGFR-L858R-T790M. CCSP-rtTA. Tet-O-Cre. Floxed WT. C tnnb1. Excised Ctnnb1 (lung). B. 1. 4. 3. EGFR-L858R-T790M. Actin.

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EGFR-L858R-T790M

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  1. A 1 2 3 4 EGFR-L858R-T790M CCSP-rtTA Tet-O-Cre Floxed WT Ctnnb1 Excised Ctnnb1 (lung) B 1 4 3 EGFR-L858R-T790M Actin Supplementary Figure S6. Generation of conditional, lung-specific Ctnnb1knockout/EGFR-L858R-T790M (EGFRTL) transgenic mice. (A) PCR Genotype from tail DNA (B) Expression of EGFR-L858R-T790M in lung tissues. (A) and (B) Mice are: 1. CCSP-rtTA/Cre/Ctnnb1F/F; 2. EGFRTL/CCSP-rtTA/Ctnnb1F/+; 3. EGFRTL/CCSP-rtTA/Cre/Ctnnb1F/F ; and 4. EGFRTL/CCSP-rtTA/Cre/Ctnnb1F/+mice.

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