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National AIDS Plans and Prevention Research: Strategies and Challenges

This document summarizes key points from the Prevention Research and National AIDS Plans conference held in Geneva, Switzerland, on June 20-21, 2005. It discusses the importance of national AIDS plans in integrating prevention research with overall strategies to combat AIDS. Key components include advocacy for prevention trials, community mobilization, coordination among stakeholders, and addressing challenges such as inadequate health systems and ethical concerns. The role of various partners, including governments and international organizations, in promoting effective prevention strategies is also highlighted.

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National AIDS Plans and Prevention Research: Strategies and Challenges

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  1. Prevention Research and National AIDS Plans20-21 June 2005Geneva, Switzerland Prof. Roy Mugerwa Department of Medicine Makerere University Medical School Prevention Research and Natioanl Aids Plans Geneva

  2. Synopsis • Overview of National AIDS Plans • Advocacy for Prevention Trials • Mobilisation/communication • Co-ordination/Networking/Harmonisation • Challenges of Prevention Trials Prevention Research and Natioanl Aids Plans Geneva

  3. Why a National AIDS Plan • A national AIDS plan provides “clear rules” - Attract partners. • A well conceived plan could be presented to development partners and other international agencies for collaboration and support. Prevention Research and Natioanl Aids Plans Geneva

  4. National AIDS Plan should: • Integrate prevention research plans within the overall National AIDS Strategy and response. • Address prevention research within the context of poverty alleviation efforts. Prevention Research and Natioanl Aids Plans Geneva

  5. National Plans should outline: • Legal framework for the conduct of biomedical research. • Regulatory bodies and ethical approval mechanisms. Prevention Research and Natioanl Aids Plans Geneva

  6. National Plans should emphasize Advocacy for prevention research • Solicit Political Commitment and Involvement • Social Mobilization -Community support and participation - Information dissem. to the Media and the Public • Involve Policy Makers. Define: - Role of National Government Bodies - The role of WHO and UNAIDS - Role of the various partners/stakeholders. Prevention Research and Natioanl Aids Plans Geneva

  7. Advocacy strategies include:- Building alliances • Mobilization of the community • Communication with policy makers, scientists, and donors • Involvement of the media • Mobilization of resources Prevention Research and Natioanl Aids Plans Geneva

  8. Mobilization of the community Participation in planning and implementation of prevention trial activities. • Input in the design of the protocol. • Input into appropriate informed consent process. • Information to the community at large on the proposed research. Prevention Research and Natioanl Aids Plans Geneva

  9. Communication • Educate people about HIV prevention trials (media, policymakers, civil society, medical community). • Engage governments, international agencies, human and civil rights bodies in dialogue on prevention trials. • Encourage women and adolescents participation but protect the vulnerable and marginalised. Prevention Research and Natioanl Aids Plans Geneva

  10. Mobilisation of Resources • Facilitate communication and accountability between funders/ stakeholders and scientists. • Facilitate communication/discussion between regional and country HIV/AIDS leaders and WHO/UNAIDS, AAVP Prevention Research and Natioanl Aids Plans Geneva

  11. Involve the Media • Advocate for HIV prevention research but manage expectations. • Focus on HIV prevention trials but not ignore other prevention (TB, ABC). • Prevention trials are designed for and tested in the regions of the world where they are most needed. Prevention Research and Natioanl Aids Plans Geneva

  12. Co-ordination/Networking • Create National and Regional frameworks to support Prevention Trials • Harmonise guidelines across regions. Prevention Research and Natioanl Aids Plans Geneva

  13. Harmonisation of guidelines across regions: • Promote development of regional networks to discuss/co-ordinate capacity building. • Harmonise training for NRA and ethics committees: to simplify the review process. • Establish Regional Task Forces to develop guidelines for regulatory review of vaccines. Prevention Research and Natioanl Aids Plans Geneva

  14. Harmonisation (Cont’d) • Incorporate general principles and policies for treatment and care for intercurrent infections. • Outline national policies on treatment of study volunteers who seroconvert during trials. Prevention Research and Natioanl Aids Plans Geneva

  15. Challenges in Conducting HIV Prevention Trials in Developing Countries • Inadequate health care outside the context of research. • Excellent services for trial volunteers with poor health services in communities. • Improve infrastructures as part of research agenda. • Build long term sustainable capacity – financial, human Prevention Research and Natioanl Aids Plans Geneva

  16. Challenges (Cont’d) • Less developed decision making systems • Legal framework; regulatory bodies; IRBs • Ethical concerns (consent, vulnerable populations) • Cultural and language barriers. Prevention Research and Natioanl Aids Plans Geneva

  17. Challenges (Cont’d) • Political suspicions • Public mistrust/misconceptions • Media-uninformed/misinformation Prevention Research and Natioanl Aids Plans Geneva

  18. THE ROAD IS RUGGED! BUT THERE IS A WAY THANK YOU Prevention Research and Natioanl Aids Plans Geneva

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