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Prevention Research and National AIDS Plans 20-21 June 2005 Geneva, Switzerland

Prevention Research and National AIDS Plans 20-21 June 2005 Geneva, Switzerland. Prof. Roy Mugerwa Department of Medicine Makerere University Medical School. Synopsis. Overview of National AIDS Plans Advocacy for Prevention Trials Mobilisation/communication

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Prevention Research and National AIDS Plans 20-21 June 2005 Geneva, Switzerland

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  1. Prevention Research and National AIDS Plans20-21 June 2005Geneva, Switzerland Prof. Roy Mugerwa Department of Medicine Makerere University Medical School Prevention Research and Natioanl Aids Plans Geneva

  2. Synopsis • Overview of National AIDS Plans • Advocacy for Prevention Trials • Mobilisation/communication • Co-ordination/Networking/Harmonisation • Challenges of Prevention Trials Prevention Research and Natioanl Aids Plans Geneva

  3. Why a National AIDS Plan • A national AIDS plan provides “clear rules” - Attract partners. • A well conceived plan could be presented to development partners and other international agencies for collaboration and support. Prevention Research and Natioanl Aids Plans Geneva

  4. National AIDS Plan should: • Integrate prevention research plans within the overall National AIDS Strategy and response. • Address prevention research within the context of poverty alleviation efforts. Prevention Research and Natioanl Aids Plans Geneva

  5. National Plans should outline: • Legal framework for the conduct of biomedical research. • Regulatory bodies and ethical approval mechanisms. Prevention Research and Natioanl Aids Plans Geneva

  6. National Plans should emphasize Advocacy for prevention research • Solicit Political Commitment and Involvement • Social Mobilization -Community support and participation - Information dissem. to the Media and the Public • Involve Policy Makers. Define: - Role of National Government Bodies - The role of WHO and UNAIDS - Role of the various partners/stakeholders. Prevention Research and Natioanl Aids Plans Geneva

  7. Advocacy strategies include:- Building alliances • Mobilization of the community • Communication with policy makers, scientists, and donors • Involvement of the media • Mobilization of resources Prevention Research and Natioanl Aids Plans Geneva

  8. Mobilization of the community Participation in planning and implementation of prevention trial activities. • Input in the design of the protocol. • Input into appropriate informed consent process. • Information to the community at large on the proposed research. Prevention Research and Natioanl Aids Plans Geneva

  9. Communication • Educate people about HIV prevention trials (media, policymakers, civil society, medical community). • Engage governments, international agencies, human and civil rights bodies in dialogue on prevention trials. • Encourage women and adolescents participation but protect the vulnerable and marginalised. Prevention Research and Natioanl Aids Plans Geneva

  10. Mobilisation of Resources • Facilitate communication and accountability between funders/ stakeholders and scientists. • Facilitate communication/discussion between regional and country HIV/AIDS leaders and WHO/UNAIDS, AAVP Prevention Research and Natioanl Aids Plans Geneva

  11. Involve the Media • Advocate for HIV prevention research but manage expectations. • Focus on HIV prevention trials but not ignore other prevention (TB, ABC). • Prevention trials are designed for and tested in the regions of the world where they are most needed. Prevention Research and Natioanl Aids Plans Geneva

  12. Co-ordination/Networking • Create National and Regional frameworks to support Prevention Trials • Harmonise guidelines across regions. Prevention Research and Natioanl Aids Plans Geneva

  13. Harmonisation of guidelines across regions: • Promote development of regional networks to discuss/co-ordinate capacity building. • Harmonise training for NRA and ethics committees: to simplify the review process. • Establish Regional Task Forces to develop guidelines for regulatory review of vaccines. Prevention Research and Natioanl Aids Plans Geneva

  14. Harmonisation (Cont’d) • Incorporate general principles and policies for treatment and care for intercurrent infections. • Outline national policies on treatment of study volunteers who seroconvert during trials. Prevention Research and Natioanl Aids Plans Geneva

  15. Challenges in Conducting HIV Prevention Trials in Developing Countries • Inadequate health care outside the context of research. • Excellent services for trial volunteers with poor health services in communities. • Improve infrastructures as part of research agenda. • Build long term sustainable capacity – financial, human Prevention Research and Natioanl Aids Plans Geneva

  16. Challenges (Cont’d) • Less developed decision making systems • Legal framework; regulatory bodies; IRBs • Ethical concerns (consent, vulnerable populations) • Cultural and language barriers. Prevention Research and Natioanl Aids Plans Geneva

  17. Challenges (Cont’d) • Political suspicions • Public mistrust/misconceptions • Media-uninformed/misinformation Prevention Research and Natioanl Aids Plans Geneva

  18. THE ROAD IS RUGGED! BUT THERE IS A WAY THANK YOU Prevention Research and Natioanl Aids Plans Geneva

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