CD Formulation Stresses the Importance of Increased Bioavailability Excipients in Drug Formulation

1. CD Formulation Stresses the Importance of Increased Bioavailability Excipients in Drug Formulation Specializing in drug formulation, the highly specialized CRO service provider CD Formulation has accumulated abundant experience in the custom synthesis of increased bioavailability excipients. To meet the requirements of different drug research projects, excipients can be tailor-made in varied specifications and volumes. Recently, formulations has gained widespread attention because they can alter the pharmacokinetics of drugs, ultimately resulting in improved bioavailability. adding increased bioavailability excipients in drug Although new advances in drug discovery, design and development have given rise to an increasing number of drug candidates, many of them failed to enter the market because of their low bioavailability. “How to improve the solubility, bio-availability and therapeutic performance of pharmaceutical ingredients has become the top concern for the majority of drug developers,” said the Marketing Manager of CD Formulation. To overcome such challenges, traditionally several techniques have been put into trial, including solid dispersion, micronization, solvent evaporation, ordered mixing, solvent deposition inclusion, and steam-assisted granulation. With the addition of increased bioavailability excipients, some long-standing issues in this regard can be effectively resolved. Just to name a few: first, the solubility of APIs in the dosage form will be improved; second, the dissolved gastrointestinal tract can be maintained for a longer time; third, increased bioavailability excipients can even co-work with the digestion and absorption of physiological lipids in the body to promote the absorption of drugs. state of the API in the At present, three major types of Increased Bioavailability Excipients can help improve bioavailability. Carbohydrate-based parenteral excipients, such as trehalose, sucrose, mannitol, sorbitol, and maltose. Polymer excipients, such as povidone and hydroxypropyl succinate.

2. Surface Active Agent - Surfactants, for instance, polyethylene glycol glycerol can be used to prepare lipid-based formulations that significantly improve solubility and thus oral bioavailability through various self-emulsifying systems. “As a reliable partner in the drug formulation field, we are fully devoted to solving problems concerning solubility, bioavailability, and drug absorption. Our custom bioavailability excipients is worth a try in every way.” synthesis service for increased Please https://www.formulationbio.com/products/increased-bioavailability- excipients.html to learn more. visit About Combining robust expertise and years of experience, CD Formulation is undoubtedly a good partner for drug developers who urgently need to overcome drug formulation and delivery challenges. Whether it’s small or large molecule therapeutics, CD Formulation is capable of troubleshooting to step up efforts for customers toward a quicker drug formulation path.