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Updates on Clinical Trials: RTOG Membership and High-Priority Cancer Trials (June 2005)

This document outlines the latest updates on clinical trials and consortium membership as of June 24, 2005. Key participants in the consortium include UPMC McKeesport, Mercy Hospital, UPMC Murtha, Somerset Cancer Center (pending), and Jameson Hospital (pending). It highlights high-priority trials such as RTOG 0420 for GBM, RTOG 0235 for NSCLC, RTOG 0214 for PCI after chemoradiotherapy, and NSABP B39/RTOG 0431 comparing whole vs. partial breast irradiation. Various trials are currently undergoing IRB review with anticipated approvals in the coming months.

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Updates on Clinical Trials: RTOG Membership and High-Priority Cancer Trials (June 2005)

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  1. Clinical Trials Update June 24th 2005

  2. Jameson, New Castle Murtha CC, Johnstown Our Consortium AGH UPMC Hillman Somerset Mercy UPMC McKeesport

  3. RTOG Membership • UPMC McKeesport (February 2005) • Mercy Hospital (Previous member) • UPMC Murtha (June 2005) • Somerset Cancer Center (pending) • Jameson Hospital (pending)

  4. The Clinical Trials • High Priority Trials • RTOG 0420: • TMZ/XRT followed by TMZ-CPT11 for GBM • IRB approved 2/05 • Accrued 2 patients • RTOG 0235: • PET pre- & post-treatment for locally advanced NSCLC • Under IRB review, anticipate approval July/August 2005 • RTOG 0214 • PCI for NSCLC after definitive chemoradiotherapy • IRB approved

  5. Clinical Trials (cont…) • NSABP B39/ RTOG 0431 • Whole breast irradiation vs. Partial breast irradiation for early stage breast cancer • Currently under IRB review • CDRP Lung (Wynn) • Amifostine to minimize treatment breaks for NSCLC • Under IRB review; anticipate approval July/August 2005

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