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Dislipemia de la enfermedad renal y fármacos hipolipemiantes

Dislipemia de la enfermedad renal y fármacos hipolipemiantes. Dislipemia de la enfermedad renal. Inmunosupresores. Diabetes. Colesterol-HDL ↓. Colesterol-LDL ↑. Triglicéridos↑↑. Progresión de la enfermedad renal. Proteinuria. %. 3%. 3%. 4%. ATC III cholesterol classification. 100.

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Dislipemia de la enfermedad renal y fármacos hipolipemiantes

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  1. Dislipemia de la enfermedad renal y fármacos hipolipemiantes

  2. Dislipemia de la enfermedad renal Inmunosupresores Diabetes Colesterol-HDL ↓ Colesterol-LDL ↑ Triglicéridos↑↑ Progresión de la enfermedad renal Proteinuria

  3. % 3% 3% 4% ATC III cholesterolclassification 100 10% 10% 9% 90 26% 24% 24% Very high, ≥190 mg/dL 80 70 High, 160-189 mg/dL 60 35% 32% 31% Borderline high, 130-159 mg/dL 50 40 Near optimal, 100-129 mg/dL 30 31% 30% 28% 20 Optimal, <100 L 10 0 None Stage 1 – 2 Stage 3 – 4 CKD stage Prevalencia de alteraciones en el colesterol-LDL en población sana y con insuficiencia renal Adapted from Snyder JJ, et al: Am J Nephrol 2009; 30(1):44-54.

  4. Supervivencia de acuerdo a la concentración de colesterol en pacientes en hemodiálisis Iseki K y col. Kidney International 2002; 61: 1887-93.

  5. Dislipemia de la enfermedad renal

  6. Dislipemia moderada con un patrón lipídico aterogénico Colesterol-HDL ↓ Colesterol-LDL = Aumento de lipoproteína (a) LDL oxidadas Triglicéridos↑↑ S S S Aumento de apoB LDL pequeñas y densas Aumento de triglicéridos postprandiales Aumento de remanentes de lipoproteínas

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