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Genetics Gregor Mendel Known as the father of genetics. Worked with garden peas. Led to knowledge of inheritance. Heredity – transmission of traits from parents to the offspring. Gene – the basic unit of inheritance. Made of DNA. In sexual reproduction: One gene from the male parent.
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Genetics • Gregor Mendel • Known as the father of genetics. • Worked with garden peas. • Led to knowledge of inheritance. • Heredity – transmission of traits from parents to the offspring. • Gene – the basic unit of inheritance. • Made of DNA. • In sexual reproduction: • One gene from the male parent. • One gene from the female parent. • Why you have two copies of same chromosome.
Alleles – alternate forms of a gene. • Ex: seed color (yellow, green seed) • Dominant and Recessive alleles • Dominant alleles – an allele that masks the presence of another allele. • Always use capital letters. • Recessive alleles – an allele that is being masked by the dominant allele. • Always use lower-case letters. • Homozygous – when both alleles are the same (homo = same). • Homozygous Dominant (AA) or homozygous recessive (aa) • Heterozygous – when both alleles are NOT the same (Hetero = different) • Heterozygous dominant (Aa)
Genotype – genetic makeup of an organism. • Ex: AA, Aa, aa • Geno = genes, genetics • Phenotype – physical appearance of an organism. • Ex: tall, yellow, wrinkled • Pheno = physical • Mendel’s work • Three Principles: • Principle of dominance – an allele masks another allele. • Principle of Segregation – two alleles for a characteristics separate during gamete formation.
Principle of Independent Assortment – alleles for different characteristics (genes) are distributed to gametes independently. • Punnett Squares – used to describe the ratio of expected outcomes of a genetic cross. • Monohybrid cross – (mono meaning one) 1 trait is crossed. • Have two alleles for each gene. • Ex: T = tall, dom t = short TT x tt (parents)
More ex: TT x Tt Tt x Tt • Testcross – an individual with unknown genotype is crossed with a homozygous recessive individual. • Ex: rabbit color B = black, dom b = brown BB x bb Bb x bb • If any brown rabbits then the parents were heterozygous, if not then they were homozygous.
Incomplete dominance – when one allele does not completely mask another. • The organism shows a blend of the two. • Ex: Japanese 4 o’clocks R = red W = white RR x WW RW = pink • Codominance – when both alleles contribute to the phenotype of the organism (no blending). • Ex: cattle color R = red r = white RR x Rr Rr = roan • Polygenic traits – traits controlled by two or more genes. (poly = many)
Sex-linked traits – trait occurs only on a sex chromosome. • Ex: colorblindness XX = female B = normal, dom XY = male b = colorblindness XBXB = normal female XBXb = normal female, carrier XbXb = colorblind female XBY = normal male XbY = colorblind male XBXb x XBY
Blood types: • A blood = IAIA or IAi • B blood = IBIB or IBi • AB blood = IAIB • O blood = ii • Dihybrid Crosses – two genes are crossed at the same time. • Ex: seed color and texture P = purple kernel, dom P = yellow kernel, rec S = smooth, dom S = wrinkled PpSs x PpSs (remember Foil – for all possible combinations of gametes)