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Comparative Analysis of Unstimulated and LPS-Stimulated Immune Responses in Cytokine Production

This study examines the immune responses of unstimulated and LPS-stimulated macrophages by measuring marker expression and cytokine levels, specifically focusing on IFN-gamma, IL-12, and COX-2. The data highlights the changes in CD14 and CD86 expression under different stimulation conditions, providing insight into macrophage activation and polarization. Results indicate that LPS stimulation significantly enhances cytokine production and surface marker expression, which could have implications for understanding immune responses in infections and inflammation.

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Comparative Analysis of Unstimulated and LPS-Stimulated Immune Responses in Cytokine Production

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  1. A. Unstimulated IFNg + LPS-stimulated 0.1% 0% 10.8% 0% IL-12 PE 0.1% 0.4% CD14 FITC B. 4.1% 25.1% 1.8% 0.05% COX-2 PE CD86 APC 6.8% 4.72%

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