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Wuchereria bancrofti and Brugia malayi

Wuchereria bancrofti and Brugia malayi. Kylie Cowdin. Geographic Range. Life Cycle of W. bancrofti. Morphology.

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Wuchereria bancrofti and Brugia malayi

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  1. Wuchereriabancroftiand Brugiamalayi Kylie Cowdin

  2. Geographic Range

  3. Life Cycle of W. bancrofti

  4. Morphology • Adult worms are long and slender with a smooth cuticle and bluntly rounded ends. Their head is slightly swollen and bears two circles of well-defined papillae. Males are about 4cm long and 100µm wide. Females are 6 to 10cm long and 300µm wide. Microfilaria of W. bancrofti

  5. Pathology • Asymptomatic phase • Inflammatory (acute) phase • Fever, chills, skin infections, painful lymph nodes, tender skin • Obstructive (chronic) phase • Lymph varices, lymph scrotum, hydrocele, chyluria, elephantiasis

  6. Diagnosis and Treatment • Diagnosis: • Blood smears, PCR, ultrasonography, X-rays • Treatment: • Cleansing the skin, surgery, drugs (DEC, ivermecting, albendazole)

  7. Prevention/Control • Insect repellents, mosquito nets, education • Sri Lanka has eradicated this disease as of April, 2011

  8. Brugiamalayi • Morphology: • Males are 13.5-20.5mm long and 70-80µm wide. • Females are 80-100mm long and 240-300µm wide. • Life cycle • Pathology • Diagnosis/Treatment • Control • Mosquito eradication and herbicides

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