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Diseases Of The Heart. dr shabeel pn. Heart Failure. Heart failure is a clinical syndrome Heart is unable to pump sufficient blood to meet the needs of the tissues Heart failure is the number 1 DRG for hospitalization in people over 65 years. Etiology of Heart Failure. CAD
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Diseases Of The Heart dr shabeel pn
Heart Failure • Heart failure is a clinical syndrome • Heart is unable to pump sufficient blood to meet the needs of the tissues • Heart failure is the number 1 DRG for hospitalization in people over 65 years
Etiology of Heart Failure • CAD • Systemic or pulmonary hypertension • Cardiomyopathy • Valvular disease • Septal defects • Myocarditis
Dysrhythmias • Hypervolemia • Metabolic disorders • Autoimmune disorders • Anemia in the elderly
Pathophysiology Of Heart Failure • Decreased amount of blood ejected from ventricles • Stimulation of SNS - increases myocardial workload or O2 demand • Ventricular hypertrophy • Decreased renal perfusion
Activation of Renin-Angiotensin-Aldosterone System • Renin interacts with Angiotensinogen to produce Angiotensin I • Angiotensin I converts to Angiotensin II • Angiotensin II stimulates release of Aldosterone
Blood backs up in left atrium and pulmonary veins • Increased hydrostatic pressure forces fluid out of pulmonary capillaries into alveoli and interstitial spaces • Right ventricle dilates due to increased pulmonary pressures (pulmonary HTN) • Engorgement of venous system extends backwards into systemic veins and organs
Right ventricular failure usually follows left ventricular failure • Right ventricular failure can occur solely without left ventricular failure – cor pulmonale • Heart failure can affect systolic function or diastolic function
Clinical Manifestations Of Left Ventricular Failure (LVF) • Dyspnea • Dyspnea on exertion (DOE) • Orthopnea • Paroxysmal nocturnal dyspnea (PND) • Cough • Crackles • Hypoxia, cyanosis • Tachycardia, palpitations
S3, S4, murmurs • Weak, thready pulses • Fatigue • Pale, cool, clammy skin • Restlessness, anxiety, confusion • Nocturia, oliguria • Decreased GFR, increased creatinine
Clinical Manifestations of Right Ventricular Failure (RVF) • Elevated JVD • Positive HJR • Hepatomegaly, splenomegaly • Ascites • Anorexia, nausea, constipation
Sacral edema • Peripheral edema • Anasarca • Weight gain • Decreased activity tolerance
Acute Pulmonary Edema • Life threatening situation • Large accumulation of fluid in lungs • Manifestations • Severe dyspnea, sense of suffocation • Cough, large amounts of frothy, blood tinged sputum • Wheezing and coarse crackles • Cyanosis
New York Heart Association’sFunctional Classification of Heart Disease • Class I – Ordinary activity does not cause symptoms • Class II – Slight limitation of ADLs • Class III – Comfortable at rest but any activity causes symptoms • Class IV – Symptoms at rest
Diagnostic Findings With Heart Failure • Echocardiogram with Doppler flow studies • Chest x-ray • ECG • B-Type Natriuretic Peptide (BNP)
BUN and creatinine • T4 and TSH • Liver function tests • Stress testing or cardiac cath
Objectives In Treating Heart Failure • Identify and eliminate the precipitating cause • Reduce the workload on the heart • Enhance patient and family coping with lifestyle changes
Medical Management of Heart Failure • Exercise • Bed rest in upright position in acute and refractory stages • Regular exercise program • Oxygen therapy • Dietary restrictions • Sodium restriction • Fluid restriction
Cardiac resynchronization – biventricular pacing (Medtronic InSyn) • Mechanical assist devices • Transplantation
Pharmacologic Management of Heart Failure • ACE inhibitors • Vasodilate • Promote diuresis • Drugs – Vasotec, Captopril, Zestril, • Angiotensin II Receptor Blockers (ARBs) • Prescribed when patient intolerant of ACE-I • Drugs – Diovan, Aticand
Beta1 Blockers • Decrease cytotoxic effects of constant stimulation of SNS • Decrease workload by decreasing heart rate • Drugs - Coreg, Lopressor, Atenolol
Vasodilators • Cause venous dilation • Cause arterial dilation • Drugs – Nitrates ie. Isordil (isosorbide) and other meds ie. Apresoline (hydralazine); BiDil ( isosorbide & hydralazine combination)
Diuretics • Control Na and H2O retention • Three types • Potassium sparing –Aldactone (spironalactone), Inspra (eplerenone) • Loop diuretics – Lasix (furosemide) • Thiazide diuretics – Zaroxolyn (metolazone), HCTZ (hydrochlorazide) • Monitor for hypotension, lyte imbalances and dehydration, worsening renal failure
Cardiac glycosides • Increase force of myocardial contraction and slow conduction through AV node • Drugs – Lanoxin (digoxin), Primacor, Inocor • Precautions with Lanoxin administration • Decreased renal function slows elimination • Will need to decrease dose with certain meds ie. amiodarone, erythromycin, quinidine • Usual dose – 0.125 mg to 0.5 mg (PO,IV,IM)
Lanoxin toxicity – Therapeutic level 0.5-2.0 ng/mL • Symptoms – anorexia, N/V, fatigue, H/A, yellow or green halos, new dysrhythmias • Reversal – hold dose or administer Digibind (digoxin immune FAB) • Nursing considerations for Lanoxin administration • Assess heart rate for 1 min • Give after breakfast • Monitor for hypokalemia
Calcium channel blockers • Contraindicated with severe systolic dysfunction • Drugs – Norvasc, Cardizem, Procardia
Natrecor (nesiritide) • Indicated for the IV treatment of clients with acutely decompensated congestive heart failure with dyspnea at rest • Manufactured from E-coli • Effects - dilates veins and arteries, suppresses Aldosterone • Administration - IV bolus, then drip for 48 hrs • Contraindications - systolic pressure <90mm Hg, binds with Heparin • Side effects - hypotension, VT, HA, nausea • Incompatible with Heparin in same line
Medical Management Of Pulmonary Edema • Sit patient in high Fowlers with legs and feet dependent • Oxygen • Morphine • Diuretics • Other meds as with heart failure
Nursing Interventions For The Client With Heart Failure • Monitor and manage potential complications • Assess cardiovascular status frequently • Vital signs • Heart sounds • Degree of JVD & HJR • All peripheral pulses
Assess respiratory status frequently • Lung sounds • Assess degree of dyspnea • Assess O2 sats • Assess renal status • I&O • BUN & Cr • Assess for nocturia
Assess GI system • HJR • Ascites • Appetite and constipation • Monitor fluid status closely • Daily weights • I&O • Peripheral and sacral edema
Reduce fatigue • Promote activity tolerance • Control anxiety • Referrals • Teach client and family
Client and Family Teaching Related to Heart Failure • Weigh daily • 2-3 gm Na diet • Fluid restrictions • Meds and side effects
Signs and symptoms to report to physician • Weight gain • Loss of appetite • Syncopy or palpitations • Worsening SOB • Persistent cough
Expected Outcomes • Maintains or improves cardiac function • Maintains or increases activity tolerance • Adheres to self-care program • Absence of complications
Cardiomyopathy • Disease of the myocardium which affects its function • Three major types of cardiomyopathy • Dilated - DCM • Hypertropic - HCM • Restrictive
Dilated Cardiomyopathy • Contractility decreases and ventricles dilate. Affects systolic function. • Etiology – viral myocarditis, toxins, alcohol, pregnancy, ischemia
Clinical manifestations same as with LVF • Dx tests – ECHO, endomyocardial biopsy, ECG, chest x-ray, blood chemistries • Tx – same as with LVF; tx dysrhythmias; heart transplant
Hypertropic Cardiomyopathy • Myocardium increases in size and mass • Reduces inner cavity of ventricles and ventricles take longer to relax and fill. Affects diastolic function • Etiology – genetic, HTN, and hypoparathyroidism
Appears most often in young adults • Clinical manifestations – sudden cardiac death; dyspnea, palpitations, dizziness • Dx tests – radionuclide scans, ECHO, chest x-ray, ECG • Tx – Beta blockers and Ca channel blockers. Avoid meds that decrease preload or increase contractility (Lanoxin). Tx dysrhythmias - may insert ICD
Restrictive Cardiomyopathy • Ventricle walls are rigid and do not stretch normally during filling. Cardiac output decreases. Affects diastolic function. • Etiology - Amylodiosis, Sarcoidosis
Clinical manifestations – fatigue, activity intolerance, dyspnea and other symptoms of LVF • Dx tests – same as other cardiomyopathies • Tx – similar to hypertropic cardiomyopathy; tx dysrhythmias. Also tx underlying cause