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Aim: How does the shape of the protein determine its function ?

Aim: How does the shape of the protein determine its function ?. HW 10 Text read pages 346-348 Pg 348 ans Q# 2,3. Transcription and Translation. Nucleus. Messenger RNA. mRNA. Lysine. Phenylalanine. tRNA. Transfer RNA. Methionine. Ribosome. Start codon. mRNA. Go to Section:.

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Aim: How does the shape of the protein determine its function ?

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  1. Aim: How does the shape of the protein determine its function ? HW 10 Text read pages 346-348 Pg 348 ans Q# 2,3

  2. Transcription and Translation Nucleus Messenger RNA mRNA Lysine Phenylalanine tRNA Transfer RNA Methionine Ribosome Start codon mRNA Go to Section:

  3. Transcription • DNA is copied in the nucleus • Complimentary strand is mRNA Adenine (DNA and RNA) Cystosine (DNA and RNA) Guanine(DNA and RNA) Thymine (DNA only) Uracil (RNA only)

  4. Translation Section 12-3 The Polypeptide “Assembly Line” Growing polypeptide chain Ribosome tRNA Lysine tRNA mRNA Completing the Polypeptide . mRNA Translation direction Ribosome Go to Section:

  5. The characteristics of a cell depends upon the proteins that are synthesized Normal Hemoglobin

  6. Sickle Cell hemoglobin

  7. Normal rbc Sickle rbc What is the function of rbc, how is the function affected ?

  8. Inheritance of Sickle Trait

  9. Reading for Sickle Cell Disease http://genetics-education-partnership.mbt.washington.edu/class/activities/HS/sickle-back.htm

  10. HBB: The Gene Associated with Sickle Cell Anemia Official Gene Symbol: HBB Name of Gene Product: hemoglobin, beta Alternate Name of Gene Product: beta globin Locus: 11p15.5 - The HBB gene is found in region 15.5 on the short (p) arm of human chromosome 11.

  11. Bone marrow transplant can cure Sickle Cell Anemia Sickle Cell Information Center News Page • This procedure replaces bone marrow affected by sickle cell anemia with healthy bone marrow from a donor who doesn't have the disease. It can be a cure, but the procedure is risky, and it's difficult to find suitable donors. Researchers are still studying bone marrow transplants for people with sickle cell anemia. Currently, the procedure is recommended only for people who have significant symptoms and problems from sickle cell anemia.

  12. Back to the question: How does the shape of the protein determine its function ? (refer to the shape of the protein hemoglobin in sickle cell)

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