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This case presentation discusses the management of a 49-year-old asymptomatic male diagnosed with HIV since 1986, with a current CD4 count of 400. Despite being on an unconventional pill regimen involving ABC/3TC and a half-dose of RTV/DRV/RGV/NVP, the patient maintains a viral load of less than 39 copies/mL. The presentation explores the implications of this treatment strategy, the roles of various antiretroviral drugs including DRV, etravirine, TDF/FTC, and maraviroc, and encourages thoughtful discussion on optimizing HIV therapy in complex cases.

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VIRTUAL MEDZONE

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  1. VIRTUAL MEDZONE Your Resource for HIV Related Innovative Medical Communication

  2. HIV CASE PRESENTATIONS Anita Rachlis MD FRCPC Ken Logue MD David Fletcher MD FRCPC

  3. CASE 1 • 49 yo man • HIV+ 1986 • CD4 400 • Asymptomatic

  4. CASE 1

  5. CASE 1

  6. CASE 1 GENOTYPE MAR/03

  7. CASE 1

  8. CASE 1 APRIL 2011 • Patient informs physician of OD pill taking for the last year despite a bid script!!!! • ABC/3TC/ ½ dose RTV/DRV/RGV/NVP • Despite this…HIV Viral Load<39!!! WHAT WOULD YOU DO?

  9. CASE 1 GENOTYPE MAR/03

  10. CASE 1 • ODABC/3TC/RTV 100mg/DRV 1200mg/RGV 800 mg/ETV 400mg ?Role Of OD DRV ?Role of Etravirine ?Role of TDF/FTC ?Role of Maraviroc

  11. CASE 1 • 49 yo man • HIV+ 1986 • CD4 400 • Asymptomatic

  12. CASE 1 • 49 yo man • HIV+ 1986 • CD4 400 • Asymptomatic

  13. CASE 1 • 49 yo man • HIV+ 1986 • CD4 400 • Asymptomatic

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