Systematic Mapping of Viral and Host Protein Interactions

Mar 02, 2025

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This research article by O.R. Rosen et al. published in Nature presents a comprehensive analysis of binary interactions and protein complex associations between viral and host proteins. The study sheds light on the intricate relationships that drive viral infection processes and host responses.

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Systematic Mapping of Viral and Host Protein Interactions

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Systematic mapping of binary interactions and protein complex associations between viral and host proteins. O R-Rosen et al. Nature000, 1-5 (2012) doi:10.1038/nature11288

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Abundant taxa in the human microbiome that have been metagenomically and taxonomically well defined in the HMP population. C Huttenhower et al. Nature 486 , 207 - 214 (2012) doi:10.1038/nature 11234.

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Analysis of the TbpA–TbpB–(holo)hTF triple complex by negative stain electron microscopy. N Noinaj et al . Nature 000 , 1 - 6 (2012) doi:10.1038/nature10823.

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Study region and trends of elevation differences between ICESat and SRTM over 2003–08. A Kääb et al. Nature 488 , 495-498 (2012) doi:10.1038/nature11324.

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SHARP1 is a suppressor of invasion, migration and metastasis by inhibiting HIFs. M Montagner et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11207.

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Structural analysis of P[14] VP8*–A-type HBGA interactions. LY Hu et al . Nature 000 , 1 - 4 (2012) doi:10.1038/nature10996.

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Proinflammatory mediators directly promote HGF– CDK4(R24C) melanoma cell dedifferentiation leading to impaired recognition by gp100-specific CTLs. J Landsberg et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11538.

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The membrane-integrated domain of BcsA–BcsB. JLW Morgan et al. Nature 000 , 1 - 6 (2012) doi:10.1038/nature 11744.

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H Cho et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11048

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Expression of the mgtC coding region inside macrophages is dependent on its leader region’s ability to senseATP, a property required for Salmonella virulence. E-J Lee & EA Groisman . Nature 486 , 271 - 275 (2012) doi:10.1038/nature 11090.

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Gene-expression patterns for 121 putative candidate genes, and tissue distribution of NDRs. P. van der Harst et al. Nature 000 , 1 - 7 (2012) doi:10.1038/nature 11677.

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Basic experimental protocols and selective labelling of DG cells by ChR2–EYFP. X Liu et al . Nature 000 , 1 - 8 (2012) doi:10.1038/nature11028. Note: This figure is from a near-final version AOP and may change prior to final publication in print/online.

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T Großkopf et al. Nature 000 , 1-4 (2012) doi:10.1038/nature11338

Relative abundance of various phylotypes of diazotrophic bacteria from the same stations as the N 2 -fixation rate measurements, estimated with TaqMan nifH gene assays. T Großkopf et al. Nature 000 , 1-4 (2012) doi:10.1038/nature11338.

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W Zheng et al. Nature 489 , 406-408 (2012) doi:10.1038/nature11446

Composite colour image of MACS J1149.6 + 2223 made from multiband data. W Zheng et al. Nature 489 , 406-408 (2012) doi:10.1038/nature11446.

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DTW Jones et al. Nature 000 , 1-6 (2012) doi:10.1038/nature11284

Integration of mutation, expression and methylation data shows differential regulation of TBR1 and EOMES in medulloblastoma. DTW Jones et al. Nature 000 , 1-6 (2012) doi:10.1038/nature11284.

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BA Methé et al . Nature 486 , 215 - 221 (2012) doi:10.1038/nature 11209

Rates of gene and OTU discovery from HMP taxonomic and metagenomic data. BA Methé et al . Nature 486 , 215 - 221 (2012) doi:10.1038/nature 11209.

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B-K Koo et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11308

RNF43 suppresses the Wnt/ b -catenin pathway by reducing surface levels of frizzled receptors. B-K Koo et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11308.

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Systematic Mapping of Viral and Host Protein Interactions

Systematic Mapping of Viral and Host Protein Interactions

Presentation Transcript

C Huttenhower et al. Nature 486 , 207 - 214 (2012) doi:10.1038/nature 11234

N Noinaj et al . Nature 000 , 1 - 6 (2012) doi:10.1038/nature10823

A Kääb et al. Nature 488 , 495-498 (2012) doi:10.1038/nature11324

M Montagner et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11207

LY Hu et al . Nature 000 , 1 - 4 (2012) doi:10.1038/nature10996

J Landsberg et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11538

JLW Morgan et al. Nature 000 , 1 - 6 (2012) doi:10.1038/nature 11744

Y-C Wang et al . Nature 000 , 1 - 4 (2012) doi:10.1038/nature10938

JLW Morgan et al. Nature 000 , 1 - 6 (2012) doi:10.1038/nature 11744

D Li et al. Nature 000 , 1 - 4 (2012) doi:10.1038/nature 12179

K Shen et al. Nature 492 , 271-275 (2012) doi:10.1038/nature11726

H Cho et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11048

E-J Lee &amp; EA Groisman . Nature 486 , 271 - 275 (2012) doi:10.1038/nature 11090

P. van der Harst et al. Nature 000 , 1 - 7 (2012) doi:10.1038/nature 11677

X Liu et al . Nature 000 , 1 - 8 (2012) doi:10.1038/nature11028

T Großkopf et al. Nature 000 , 1-4 (2012) doi:10.1038/nature11338

S Turcan et al . Nature 000 , 1 - 5 (2012) doi:10.1038/nature10866

W Zheng et al. Nature 489 , 406-408 (2012) doi:10.1038/nature11446

DTW Jones et al. Nature 000 , 1-6 (2012) doi:10.1038/nature11284

BA Methé et al . Nature 486 , 215 - 221 (2012) doi:10.1038/nature 11209

B-K Koo et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11308

E-J Lee & EA Groisman . Nature 486 , 271 - 275 (2012) doi:10.1038/nature 11090