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HEART-LUNG TRANSPLANTATION

HEART-LUNG TRANSPLANTATION. Overall. ISHLT. 2006. J Heart Lung Transplant 2006;25: 880-892. NUMBER OF HEART-LUNG TRANSPLANTS REPORTED BY YEAR.

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HEART-LUNG TRANSPLANTATION

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  1. HEART-LUNG TRANSPLANTATION Overall ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  2. NUMBER OF HEART-LUNG TRANSPLANTS REPORTED BY YEAR NOTE: This figure includes only the heart-lung transplants that are reported to the ISHLT Transplant Registry. As such, this should not be construed as evidence that the number of heart-lung transplants worldwide has declined in recent years. ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  3. AVERAGE CENTER VOLUMEHeart-LungTransplants: January 1, 1998 - June 30, 2005 ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  4. DISTRIBUTION OF HEART-LUNG TRANSPLANTS BY CENTER VOLUMEHeart-Lung Transplants: January 1, 1998 - June 30, 2005 ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  5. DISTRIBUTION OF HEART-LUNG TRANSPLANTS BY LUNG CENTER VOLUMELung Transplants: January 1, 1998 - June 30, 2005 ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  6. HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival (Transplants: January 1982 - June 2004) Half-life = 3.1 years Conditional Half-life = 8.7 years N=3,086 Survival (%) N alive at 18 years = 18 ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  7. HEART-LUNG TRANSPLANTATION Adult Recipients ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  8. DIAGNOSIS IN ADULT HEART-LUNG TRANSPLANTS (1/1982-6/2005) “Other” includes cancer, LAM, OB, sarcoidosis, bronchiectasis ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  9. DIAGNOSIS IN ADULT HEART-LUNG TRANSPLANTS(Transplants: January 1982 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  10. DIAGNOSIS IN ADULT HEART-LUNG TRANSPLANTS BY ERA “Other” includes OB (non-ReTX), Bronchiectasis, Sarcoidosis ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  11. ADULT HEART-LUNG TRANSPLANTATIONIndications By Year (%) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  12. ADULT HEART-LUNG TRANSPLANTATIONIndications By Year (Number) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  13. HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival for Adult Recipients(Transplants: January 1982 - June 2004) Half-life = 3.5 years Conditional Half-life = 9.0 years N=2,496 Survival (%) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  14. HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival for Adult Recipients by Era(Transplants: January 1982 - June 2004) Half-life: 1982-1995 = 3.1 years; 1996-1999 = 3.6 years; 2000-6/2005 = 5 years Conditional Half-life: 1982-1995 = 8.9 years Survival (%) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  15. ADULT HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival By Diagnosis(Transplants: January 1990 – June 2004) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  16. ADULT HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival By Diagnosis Conditional on Survival to 1 Year(Transplants: January 1990 – June 2004) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  17. ADULT HEART-LUNG RECIPIENTS Functional Status of Surviving Recipients (Follow-ups: April 1994 – June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  18. ADULT HEART-LUNG RECIPIENTSEmployment Status of Surviving Recipients(Follow-ups: April 1994 – June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  19. ADULT HEART-LUNG RECIPIENTS: Rehospitalization Post-transplantof Surviving Recipients(Follow-ups: April 1994 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  20. ADULT HEART-LUNG RECIPIENTS Induction ImmunosuppressionFor transplants between January 2001 through June 2005 ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  21. ADULT HEART-LUNG RECIPIENTSInduction Immunosuppression (Transplants: January 2000 - December 2004) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  22. ADULT HEART-LUNG RECIPIENTSInduction Immunosuppression (Transplants: January 2000 - December 2004) Any Induction Polyclonal ALG/ATG OKT3 IL2R-antagonist ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  23. ADULT HEART-LUNG RECIPIENTSMaintenance Immunosuppression at Time of Follow-upFor follow-ups between January 2001 through June 2005 NOTE: Different patients are analyzed in Year 1 and Year 5 ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  24. ADULT HEART-LUNG RECIPIENTSMaintenance Immunosuppression Drug Combinations at Time of Follow-upFor follow-ups between January 2001 through June 2005 NOTE: Different patients are analyzed in Year 1 and Year 5 ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  25. POST-HEART-LUNG TRANSPLANT MORBIDITY FOR ADULTSCumulative Prevalence in Survivors within 1 Year Post-Transplant (Follow-ups: April 1994 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  26. POST-HEART-LUNG TRANSPLANT MORBIDITY FOR ADULTSCumulative Prevalence in Survivors within 5 Years Post-Transplant (Follow-ups: April 1994 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  27. Freedom from Coronary Artery Vasculopathy For Adult Heart-Lung Recipients(Follow-ups: April 1994-June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  28. Freedom from Bronchiolitis Obliterans For Adult Heart-Lung Recipients(Follow-ups: April 1994-June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  29. Freedom from Severe Renal Dysfunction*For Adult Heart-Lung Recipients(Follow-ups: April 1994-June 2005) *Severe renal dysfunction = Creatinine > 2.5 mg/dl, dialysis or renal transplant ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  30. MALIGNANCY POST-HEART-LUNG TRANSPLANT FOR ADULTSCumulative Prevalence in Survivors(Follow-ups: April 1994-June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  31. Freedom from MalignancyFor Adult Heart-Lung Recipients(Follow-ups: April 1994- June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  32. ADULT HEART-LUNG TRANSPLANT RECIPIENTS: Cause of Death(Deaths: January 1992 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  33. HEART-LUNG TRANSPLANTATION Pediatric Recipients ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  34. AGE DISTRIBUTION OF PEDIATRIC HEART-LUNGRECIPIENTS (Transplants: January 1982 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  35. AGE DISTRIBUTION FOR DONORS OF PEDIATRIC HEART-LUNG RECIPIENTS(Transplants: January 1982 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  36. AGE DISTRIBUTION OF PEDIATRIC HEART-LUNG RECIPIENTSBy Year of Transplant Number of Transplants NOTE: This figure includes only the heart transplants that are reported to the ISHLT Transplant Registry. As such, this should not be construed as evidence that the number of pediatric heart-lung transplants worldwide has declined in recent years. ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  37. AGE DISTRIBUTION OF PEDIATRIC HEART-LUNG RECIPIENTSBy Era of Transplant Percentage of Transplants ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  38. NUMBER OF CENTERS REPORTING PEDIATRIC HEART-LUNG TRANSPLANTS ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  39. “Other” includes Bronchiectasis, Alpha-1, and OB (non-ReTX) DIAGNOSIS IN PEDIATRIC HEART –LUNG TRANSPLANT RECIPIENTS (Age: 11-17 Years) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  40. PEDIATRIC HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival By Diagnosis(Transplants: January 1990 – June 2004) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  41. PEDIATRIC HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival(Transplants: January 1982 - June 2004) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  42. PEDIATRIC HEART-LUNG TRANSPLANTATION Kaplan-Meier Survival by Era(Transplants: January 1982 - June 2004) Survival (%) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  43. PEDIATRIC HEART-LUNG TRANSPLANT RECIPIENTS: Cause of Death(Deaths: January 1992 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

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