Download
heart lung transplantation n.
Skip this Video
Loading SlideShow in 5 Seconds..
HEART-LUNG TRANSPLANTATION PowerPoint Presentation
Download Presentation
HEART-LUNG TRANSPLANTATION

HEART-LUNG TRANSPLANTATION

186 Vues Download Presentation
Télécharger la présentation

HEART-LUNG TRANSPLANTATION

- - - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript

  1. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 HEART-LUNG TRANSPLANTATION Overall

  2. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 NUMBER OF HEART-LUNG TRANSPLANTS REPORTED BY YEAR NOTE: This figure includes only the heart-lung transplants that are reported to the ISHLT Transplant Registry. As such, this should not be construed as evidence that the number of heart-lung transplants worldwide has declined in recent years.

  3. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 AVERAGE CENTER VOLUMEHeart-LungTransplants: January 1, 1998 - June 30, 2009

  4. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 DISTRIBUTION OF HEART-LUNG TRANSPLANTS BY CENTER VOLUMEHeart-Lung Transplants: January 1, 1998 - June 30, 2009

  5. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 DISTRIBUTION OF HEART-LUNG TRANSPLANTS BY LUNG CENTER VOLUMELung Transplants: January 1, 1998 - June 30, 2009

  6. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival for All Ages(Transplants: January 1990 - June 2008)

  7. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 HEART-LUNG TRANSPLANTATION Adult Recipients

  8. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 DIAGNOSIS IN ADULT HEART-LUNG TRANSPLANTS (January 1982 - June 2009) “Other” includes cancer, LAM, OB, sarcoidosis, bronchiectasis

  9. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 DIAGNOSIS IN ADULT HEART-LUNG TRANSPLANTS(Transplants: January 1982 - June 2009)

  10. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 DIAGNOSIS IN ADULT HEART-LUNG TRANSPLANTS BY ERA(Transplants: January 1982 - June 2009) “Other” includes OB (non-ReTX), Bronchiectasis, Sarcoidosis

  11. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 ADULT HEART-LUNG TRANSPLANTATIONMajor Indications By Year (%)

  12. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 ADULT HEART-LUNG TRANSPLANTATIONMajor Indications By Year (Number)

  13. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 ADULT HEART-LUNG TRANSPLANTS:AGE DISTRIBUTION BY LOCATIONTransplants between January 2000 and June 2009

  14. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 ADULT HEART-LUNG TRANSPLANTS:DIAGNOSIS DISTRIBUTION BY LOCATION Transplants between January 2000 and June 2009

  15. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 ADULT HEART-LUNG TRANSPLANTS:DONOR AGE DISTRIBUTION BY LOCATIONTransplants between January 2000 and June 2009

  16. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival for Adult Recipients(Transplants: January 1982 - June 2008)

  17. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival for Adult Recipients by Era(Transplants: January 1982 - June 2008)

  18. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 ADULT HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival By Diagnosis(Transplants: January 1990 – June 2008)

  19. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 ADULT HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival By Diagnosis Conditional on Survival to 1 Year(Transplants: January 1990 – June 2008)

  20. ADULT HEART-LUNG RECIPIENTS Cross-Sectional Analysis Functional Status of Surviving Recipients (Follow-ups: April 1994 – June 2009) ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141

  21. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 ADULT HEART-LUNG RECIPIENTSLongitudinal Analysis Functional Status of Surviving Recipients For the Same Patients(Follow-ups: April 1994 – June 2009)

  22. ADULT HEART-LUNG RECIPIENTSFunctional Status of Surviving Recipients US Recipients Only(Follow-ups: March 2005 - June 2009) ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141

  23. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 ADULT HEART-LUNG RECIPIENTSEmployment Status of Surviving Recipients(Follow-ups: April 1994 – June 2009)

  24. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 ADULT HEART-LUNG RECIPIENTS:Rehospitalization Post-transplant of Surviving Recipients(Follow-ups: April 1994 - June 2009)

  25. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 ADULT HEART-LUNG RECIPIENTS Induction ImmunosuppressionFor transplants between January 2001 through June 2009 Analysis is limited to patients who were alive at the time of the follow-up

  26. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 ADULT HEART-LUNG RECIPIENTSInduction Immunosuppression (Transplants: January 2000 - December 2008) Analysis is limited to patients who were alive at the time of the follow-up

  27. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 ADULT HEART-LUNG RECIPIENTSInduction Immunosuppression (Transplants: January 2000 - December 2008) Any Induction Polyclonal ALG/ATG OKT3 IL2R-antagonist Analysis is limited to patients who were alive at the time of the follow-up

  28. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 ADULT HEART-LUNG RECIPIENTSMaintenance Immunosuppression at Time of Follow-upFor follow-ups between January 2001 through June 2009 NOTE: Different patients are analyzed in Year 1 and Year 5 Analysis is limited to patients who were alive at the time of the follow-up

  29. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 ADULT HEART-LUNG RECIPIENTSMaintenance Immunosuppression Drug Combinations at Time of Follow-upFor follow-ups between January 2001 through June 2009 NOTE: Different patients are analyzed in Year 1 and Year 5 Analysis is limited to patients who were alive at the time of the follow-up

  30. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 POST-HEART-LUNG TRANSPLANT MORBIDITY FOR ADULTSCumulative Prevalence in Survivors within 1 Year Post-Transplant (Follow-ups: April 1994 - June 2009)

  31. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 POST-HEART-LUNG TRANSPLANT MORBIDITY FOR ADULTSCumulative Prevalence in Survivors within 5 Years Post-Transplant (Follow-ups: April 1994 - June 2009)

  32. Freedom from Coronary Artery Vasculopathy For Adult Heart-Lung Recipients (Follow-ups: April 1994-June 2009) ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141

  33. Freedom from Coronary Artery Vasculopathy For Adult Heart-Lung Recipients By Diagnosis Type (Follow-ups: April 1994-June 2009) ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 P-value comparing all = 0.2078

  34. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 Freedom from Bronchiolitis Obliterans Syndrome For Adult Heart-Lung Recipients(Follow-ups: April 1994-June 2009)

  35. Freedom from Bronchiolitis Obliterans SyndromeFor Adult Heart-Lung Recipients By Diagnosis Type (Follow-ups: April 1994-June 2009) ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 P-value comparing all = 0.7771

  36. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 Freedom from Severe Renal Dysfunction*For Adult Heart-Lung Recipients(Follow-ups: April 1994-June 2009)

  37. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 MALIGNANCY POST-HEART-LUNG TRANSPLANT FOR ADULTSCumulative Prevalence in Survivors(Follow-ups: April 1994-June 2009) * Recipients may have experienced more than one type of malignancy so sum of individual malignancy types may be greater than total number with malignancy.

  38. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 Freedom from MalignancyFor Adult Heart-Lung Recipients(Follow-ups: April 1994- June 2009)

  39. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 ADULT HEART-LUNG TRANSPLANT RECIPIENTS: Cause of Death(Deaths: January 1992 - June 2009)

  40. ADULT HEART-LUNG TRANSPLANT RECIPIENTS: Relative Incidence of Leading Causes of Death(Deaths: January 1992 - June 2009) ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141

  41. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 HEART-LUNG TRANSPLANTATION Pediatric Recipients

  42. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 AGE DISTRIBUTION OF PEDIATRIC HEART-LUNGRECIPIENTS (Transplants: January 1982 - June 2009)

  43. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 AGE DISTRIBUTION FOR DONORS OF PEDIATRIC HEART-LUNG RECIPIENTS(Transplants: January 1982 - June 2009)

  44. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 AGE DISTRIBUTION OF PEDIATRIC HEART-LUNG RECIPIENTSBy Year of Transplant Number of Transplants NOTE: This figure includes only the heart transplants that are reported to the ISHLT Transplant Registry. As such, this should not be construed as evidence that the number of pediatric heart-lung transplants worldwide has declined in recent years.

  45. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 AGE DISTRIBUTION OF PEDIATRIC HEART-LUNG RECIPIENTSBy Era of Transplant Percentage of Transplants

  46. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 NUMBER OF CENTERS REPORTING PEDIATRIC HEART-LUNG TRANSPLANTS NEED TO UPDATE

  47. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 NUMBER OF CENTERS REPORTING PEDIATRIC HEART-LUNG TRANSPLANTSStratified by center volume

  48. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 “Other” includes Bronchiectasis, Alpha-1, and OB (non-ReTX) DIAGNOSIS IN PEDIATRIC HEART-LUNG TRANSPLANT RECIPIENTS (Transplants: 1986-2008) NOTE: Unknown diagnoses were excluded from this tabulation.

  49. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART-LUNG TRANSPLANTS:AGE DISTRIBUTION BY LOCATIONTransplants between January 2000 and June 2009

  50. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART-LUNG TRANSPLANTS:DIAGNOSIS DISTRIBUTION BY LOCATION Transplants between January 2000 and June 2009