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This article explores the potential of cranberries in preventing urinary tract infections (UTIs). With a focus on the active compounds in cranberries that hinder bacterial adhesion in the bladder, the analysis reviews findings from multiple studies, indicating that cranberry products significantly reduce UTI occurrences, especially in women with recurrent infections. However, limitations such as high dropout rates, unclear optimum dosages, and varied methods of delivery highlight the need for further research. The evidence remains inconclusive, with adherence and population specificity also raising questions.
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Do Cranberries Prevent Urinary Tract Infections? Sarah Gunnell, MS, CNSD, CSP, RD,CD
Background • Urinary tract infection • Presence of bacteria in the urine • Cranberries • 90% water • Quinic acid, malic acid, and citric acid as well as glucose and fructose • Prevent bacteria from adhering to the uroepithelial cells of the bladder wall
Cochrane Review Results • Five cross-over and five parallel group studies • Cranberry juice versus placebo • Cranberry tablets versus placebo • Cranberry products significantly reduced UTI at 12 months compared to placebo and control • More effective in women with recurrent infections
Limitations • High dropout rate • Optimum dose not clear • Method of delivery not clear • Six studies not included in meta-analysis
Conclusions • Evidence is limited • Adherence is questionable • Population specific • Dosage, duration, and administration method not clear