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Impact of IFN-α Concentrations on pSTAT1 Activation in CD16+56- and CD16+56+ Cells

This study investigates the activation of pSTAT1 in various cell subtypes (CD16+56-, CD16+56+, and CD16-56+) with different concentrations of IFN-α, ranging from 0 to 10,000 u/ml. Data reveals a dose-dependent increase in pSTAT1 activation levels, measured across multiple samples. The findings contribute to understanding how varying IFN-α levels influence immune cell signaling mechanisms, which is essential for therapeutic applications in immunology and oncology.

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Impact of IFN-α Concentrations on pSTAT1 Activation in CD16+56- and CD16+56+ Cells

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  1. Supplemental Figure 1 CD16+56- CD16+56+ CD16-56+ 474 430 421 Isotype IFNa 0 u/ml 523 581 566 IFNa 1,000 u/ml 713 795 653 IFNa 3,000 u/ml 942 804 764 IFNa 10,000 u/ml 1017 847 886 pSTAT1

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