Antidiuretic Hormone (ADH) Peptide Hormone Also known as Vasopressin or Arginine Vasopressin Released by Posterior Pituitary Produced in the Hypothalamus, transported via neurons
Reabsorption of water from Kidneys. Inhibits diuresis; which is the production of urine
Collecting Duct, Distal Tubule Collecting duct with the absence of ADH is not permeable to water
Oxytocin Polypeptide Hormone First polypeptide hormone to be sequenced and synthesized. 1953 Produced and transported from the Hypothalamus to the posterior pituitary.
Uterine Contractions Target: Smooth Muscle Cells Ovaries - Milk Release Target: Mammary Gland (Breast) Notice that Oxytocin is released due to physical factors.
Alveoli stores milk Surrounded by smooth muscle cells, myoepithelial cells.
Prolactin Protein Hormone Released and produced in the Anterior Pituitary Release into the bloodstream is inhibited by Dopamine, from the Hypothalamus.
As the baby starts suckling Dopamine is inhibited Increases Prolactin release, from anterior pituitary Oxytocin – Milk release
Involved in maturation of mammary glands and milk production Pro + Lactin = Before Milk (Greek) Estrogen also increases the production and secretion of Prolactin into the system
Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) Both Glycoprotein Hormones
Both are produced in the anterior pituitary Both target the gonads (Ovaries and Testes) Produced by gonadotropes in the anterior pituitary
Sertoli Cells can release inhibin if too much testosterone is present. This inhibits FSH.
Growth Hormone (GH) Protein Hormone AKA somatotropin Stimulates the growth of bones and soft tissue. Controls the metabolism of glucose and other fuels
Promotes fat catabolism. Causes cells to switch from burning carbs to burning fat stores. Accelerates rate of glycogen stores in the liver to convert to glucose.
How does this help increase blood glucose levels?
Hypothalamus releases Growth Hormone Releasing Hormone (GHRH) when Insulin-like growth factor is too low. When levels are too high, it signals the hypothalamus to release somatostatin. This inhibits the anterior pituitary from releasing GH, Growth Hormone.
Thyroid Stimulating Hormone (TSH) Glycoprotein Hormone Targets: Thyroid Promotes the release of Thyroxine (T4) and Triiodothyroxine (T3)
Both T4 and T3 Mostly T4 (Thyroxine) T3 (Triiodothyroxine) is the more active form T4 to T3 in Liver
Adrenocorticotropic Hormone (ACTH) Peptide Hormone Stimulates adrenal cortex to release glucocorticoids (steroids) Example: cortisol
Controlled by Corticotropin-releasing hormone (CRH) Once Cortisol is released, it negatively inhibitsthe hypothalamus from releasing CRH