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URINE CONCENTRATION V BS 122 2008

URINE CONCENTRATION V BS 122 2008. Luis A Bate. F21-1. F21-2. ENDOCRINE CONTROL. Anti Diuretic Hormone (ADH) Renin-Angiotensin-Aldosterone Atrial Natriuretic Hormone (ANH) Urodilatin. F21-3. ADH SECRETION. OR. OR. BR. OR. OR. BR. ADH. OR. ↓urine volume. F 21-4. F21-5.

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URINE CONCENTRATION V BS 122 2008

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  1. URINE CONCENTRATION V BS 1222008 Luis A Bate

  2. F21-1

  3. F21-2

  4. ENDOCRINE CONTROL • Anti Diuretic Hormone (ADH) • Renin-Angiotensin-Aldosterone • Atrial Natriuretic Hormone (ANH) • Urodilatin F21-3

  5. ADH SECRETION OR OR BR OR OR BR ADH OR ↓urine volume F 21-4

  6. F21-5

  7. F12-6

  8. F12-7

  9. FLUID CONTENT OF THE BODY Age IntracellExtracell Total Young 45 30 75 Adult 40 20 60 F21-8

  10. POOLS OF FLUIDS • Intracellular • Extracellular • Plasma • Interstitial Fluid • Synovial • Cerebrospinal • Lymph • Ocular F21-9

  11. WATER BALANCE • Sources • Drinking • Food • Cellularmetabolism • Losses • Urine • Evaporation • Sweating • Respiration and tongue • Faeces F21-10

  12. MECHANISM CONTROLLING THIRST • Water in oral mucosa • Mechanical distension of the stomach F21-11

  13. REGULATION OF WATER IN THE INTRACELLULAR POOL • Passage of ions is regulated • Plasma membrane • Active transport • Electric charge • Water move by osmosis F21-12

  14. LOW OSMOLALITY REGULATION OF BLOOD OSMOLALITY HIGHOSMOLALITY • Detected by hypothalamic osmoreceptors • Increase in thirst sensation • Increase ADH secretion • Increase fluid intake • Increase permeability of renal cells • More water move into blood • Decrease blood osmolality • Detected by hypothalamic osmoreceptors • Decrease thirst sensation • Decrease ADH secretion • Decrease fluid intake • Decrease permeability of renal cells • Less water move into blood • Increase osmolality F21-13

  15. EFFECT OF ANH ON BLOOD VOLUME Increased BP in right atrium ANH Increased ANH in circulation Increased Na+ and water excretion reduce BP F21-14

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