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Investigating Fronto-Temporal Functional Connectivity in Language Processing

This study aims to analyze the functional connectivity between the left inferior frontal gyrus (LIFG) and temporal lobes during language tasks, exploring potential task modulation and anatomical connections. Tasks include phonology, semantics, and baseline comparisons among healthy English speakers using Dynamic Causal Modelling in SPM.

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Investigating Fronto-Temporal Functional Connectivity in Language Processing

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  1. Fronto-temporal functional connectivity in language Cheryl M. Capek Joseph T. Devlin

  2. Background idea + notion knows + nose The aims of the current study are: • to determine functional connectivity between the regions of LIFG and the temporal lobes • to investigate whether this is significantly modulated by task • To determine whether the functional connections correspond to anatomical fronto-temporal connections

  3. Stimuli & Design + + printlock scareglare ? *** ? *** + + freightplate pinthint ~48 15s ~48s 15s t • Phonology task (“Do the words rhyme?”) • Semantic task (“Are the words from the same category?”) e.g., frock/gown, hotel/exam • Baseline task (“Do these look the same?) e.g., pzkmr/ pzkmr, dsgnr/ mfjpt

  4. Proposal slide • 24 healthy, monolingual speakers of English • Four conditions (80 trials each) 1. rhyme decisions (rose – knows) 2. category decisions (tree – flower) 3. visual matching (prtf – prtf) 4. Fixation/rest Separated into three 8 minute runs using mixed design with jittered ISI (4-10s, mean=7) • Whole brain coverage (3x3x3 mm), TR =3, TE =50ms • Dynamic Causal Modelling (DCM), SPM

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