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FORMATS OF NIH APPLICATIONS

FORMATS OF NIH APPLICATIONS. Acknowledgment. James S. Panagis, MD, MPH Director, Orthopaedics Program NIAMS, NIH, DHHS 6701 Democracy Boulevard, #800 Bethesda, MD 20892 (P) 301-594-5055 (F) 301-480-4543 jp149d@nih.gov. NIH. 27 Institutes and Centers Budgets (FY 2005):

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FORMATS OF NIH APPLICATIONS

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  1. FORMATS OF NIH APPLICATIONS

  2. Acknowledgment James S. Panagis, MD, MPH Director, Orthopaedics Program NIAMS, NIH, DHHS 6701 Democracy Boulevard, #800Bethesda, MD 20892(P) 301-594-5055(F) 301-480-4543jp149d@nih.gov

  3. NIH • 27 Institutes and Centers • Budgets (FY 2005): • NIH = ~$28 Billion • NIAMS = ~$511 Million • > 70,000 applications in FY 2004

  4. Types of Applications • Unsolicited • Solicited • Program Announcement (PA) • Request for Applications (RFA) • Request for Contracts (RFC)

  5. NIH Receipt, Review & Award Cycles

  6. Funding Mechanisms • Training: F 31, 32, 33 • Career Development: K 01, 02, 08, 22, 23, 24, 25 • P 01 • P 30, 50, 60 • Research: R 01, 03, 15, 21, 37 • R 41, 42, 43, 44 • T 32 • U 01

  7. Medical School Residency Fellowship Junior Faculty Career T32 T32 F32 K01, K08, K22, K23, R03, R21 R01, R21, K24 Career Timeline & NIH Mechanisms

  8. What is the Right Mechanism? • Your training & experience • What you need • What you would like to do (time & amount)

  9. Career Development Award “K” Awards

  10. Mentored Research Scientist Development Award K01 http://grants.nih.gov/grants/guide/pa-files/PA-00-019.html

  11. K01 • Purpose is to develop outstanding scientists • 3 – 5 yrs of supervised research experience • 75 % effort • Ineligible if prior R01, R29, K(01,07,23), P(01,50) • Salary: Salary determined by I/C • NIAMS=$75,000)

  12. K01 • Research Dev. Support: i.e., tuition, fees & research support. Amount varies (NIAMS = $20,000) • Facilities & Admin costs: Fixed at 8% • Mentor should have independent research support (mentor is not salaried) • Standard receipt dates

  13. Mentored Clinician Scientist Development Award K08 http://grants.nih.gov/grants/guide/pa-files/PA-00-003.html

  14. K08 • Purpose is to develop clinical research scientists • Similar format/regulations to K01 • 52.3% success rate

  15. NIAMS Career Transition Award K22 http://www.niams.nih.gov/rtac/funding/grants/pa/par_02_056.pdf

  16. K22 • Provides training within a NIAMS intramural lab followed by support in an extramural institution • Ineligible if prior R01, R29, SBIR/STTR, P01, P50, K08 • Provides up to $150,000/YR for all years

  17. K22 • Intramural (Phase I): Salary based upon training &experience. • Extramural (Phase II): Salary up to $75,000. Can be supplemented. 75% effort. Up to $75,000 for research supplies. • F & A: 8% • Standard receipt dates • 40.2 % success rate

  18. Mentored Patient-Oriented Research Career Development Award K23 http://grants.nih.gov/grants/guide/pa-files/PA-00-004.html

  19. K23 • Purpose is to develop clinical researchers • 3 – 5 yrs of support; 75% effort • Same eligibility as the other K’s • Salary : Varies by I/C. May be supplemented (NIAMS = $75,000) • Res. Development Support: Up to $25,000 • F & A: 8%

  20. K23 • Mentors should have independent research support • Can not be salaried. • Standard receipt dates • 46.6 % success rate

  21. Mentored Quantitative Research Career Development Award K25 http://grants.nih.gov/grants/guide/pa-files/PA-02-127.html

  22. K25 • Purpose is to foster interdisciplinary collaboration in biomedical research by supporting career development experiences for scientists with quantitative and engineering backgrounds • 3-5 YRS of support • 75% effort • Similar format/regulations as other Ks

  23. NIAMS Small Grant Award for New Investigators R03 http://www.niams.nih.gov/rtac/funding/grants/pa/par_04_002.pdf

  24. R03 • Funding for pilot/preliminary data • Ineligible if previous/current large mechanism support, or NIAMS R21 • Receipt dates: 2/24/05, 6/24/05, 10/24/05 • Up to 3 YRS of support • Up to $50,000 direct costs/YR • Limited to 2 small grant awards/career • Lower success rate due to # of apps

  25. Exploratory/Developmental Research Grant R21

  26. R21 • Appropriate for early stages of research that are high risk because of possible failure, but if successful, may be of significant benefit • 2 YRS of support; $275,000 split over the 2 yrs

  27. R21 Program Announcements • PA-03-058: Exploratory/Developmental (R21) Bioengineering Research Grant (EBRG) http://www.niams.nih.gov/rtac/funding/grants/pa/pa_03_058.pdf • PA-03-107: NIH Exploratory/Developmental Research Grant Award (R21) http://www.niams.nih.gov/rtac/funding/grants/pa/pa_03_107.pdf

  28. Shorter Duration R01 • Prove feasibility, setting stage for what to follow in a competing continuation • Suggest 3 years • Avoids being “overly ambitious” in an R03, or if limited preliminary data, “high risk” for a longer duration R01

  29. NIH Loan Repayment Program for Clinical Researchers • Purpose: To recruit & retain clinical investigators • Re-pays up to $35,000/YR of educational loan expenses for each YR of obligated service • Also pays 39% of loan repayment to IRS • Must agree to engage in clinical research a minimum of 2 years http://www.lrp.nih.gov

  30. Tips • Contact NIH Program Officer (PO) • Read application instructions carefully • Focus on perfecting the abstract & specific aims • Communicate clearly & thoroughly • Allow time for a thorough editing & proofreading • Have knowledgeable colleagues review application • Send in supplemental progress materials, papers • Speak with NIH PO post-review • Be prepared to revise in response to critique

  31. BE PERSISTENT

  32. Resources • NIAMS Homepage: http://www.niams.nih.gov • NIH Grants Page: http://grants1.nih.gov/grants/oer.htm • “Welcome Wagon”: http://grants1.nih.gov/grants/funding/welcomewagon.htm • “Getting Started at the NIH”: http://grants1.nih.gov/grants/useful_links.htm • “Grant Writing Tips”: http://grants1.nih.gov/grants/grant_tips.htm

  33. Resources: Tutorials • How to Write a Grant Application: www.niaid.nih.gov/ncn/grants/write/write.pdf • Advice on Research Training & Career Awards: www.niaid.nih.gov/ncn/grants/advice/advice.pdf • How to Write an Application Involving Animals: www.niaid.nih.gov/ncn/clinical/researchanimals/tutorial/researchanimals.pdf • How to Write a Human Subjects Application: www.niaid.nih.gov/ncn/clinical/humansubjects/humansubjects.pdf • Annotated R01 Grant Application: www.niaid.nih.gov/ncn/grants/app/default.htm

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