1 / 18

Lung cancer: Screening & early detection

21 st Century Oncology Lung Cancer Seminar. Lung cancer: Screening & early detection. Imtiaz Ahmad, MD, FCCP 21 st Century Oncology. Prevention of lung cancer. Prevention of smoking remains to be the key to reduce the risk of lung cancer. Key points. What is lung cancer? Am I at risk?

iolani
Télécharger la présentation

Lung cancer: Screening & early detection

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. 21st Century Oncology Lung Cancer Seminar Lung cancer: Screening & early detection Imtiaz Ahmad, MD, FCCP 21st Century Oncology

  2. Prevention of lung cancer • Prevention of smoking remains to be the key to reduce the risk of lung cancer

  3. Key points • What is lung cancer? • Am I at risk? • Why get screened? • Should I start now? • Screening for lung cancer? • The testing for lung cancer • Prevention & early detection

  4. What is lung cancer? • Uncontrolled and abnormal growth of cells • The leading cause of death among men and women • 228,000 men and women in the U.S. will be diagnosed and 159,000 died of lung cancer in 2013.

  5. Am I at risk? • Tobacco and second hand smoke • Radon • Asbestos • Environment pollution • Arsenic in drinking water • Personal and family history of lung cancer • Dietary supplement e.g. beta-carotene • Radiation therapy (post-treatment in lymphoma) • Chronic lung disease (e.g. COPD, pulmonary fibrosis)

  6. Why get screened? • Early detection improve prognosis • Currently ~75% of new lung cancer patients presents at advanced stages • Survival ~50% (Stage I) vs ~2% (Stage IV) at 5 yr • Cessation of smoking remains to be only effective prevention Mountain CF. Chest 1986;89(suppl):225-233.

  7. Why get screened? • Benefits: • Can reduce the number of deaths from lung cancer • Screening in asymptomatic patients yield earlier stage of disease • Minimally invasive surgery is very helpful in asymptomatic lung nodule patients. • Risks: • May yield advanced cases of disease • Unnecessary treatment in slow growing cancer • Unnecessary tests and procedures and risk of complications

  8. Should I start now? • Treatment is most effective if you are asymptomatic • Symptoms of lung cancer • Persistent cough • Shortness of breath • Coughing up blood • Chest pain • Fatigue • Hoarseness of voice • Pneumonia • Fatigue

  9. Screening for lung cancer? • USPSTF recommends annual screening for lung cancer with low-dose computed tomography (LDCT) in • adults aged 55 to 80 years and • 30 pack-year smoking history and • currently smoke or have quit within the past 15 years. • Chest x-ray is not recommended as screening tool

  10. Screening for lung cancer? • 100 LDCT yield > 1lung cancer • 320 LDCT yield > 1life (vs. 465-601 mammogram for breast cancer) • LDCT screening yields 24% positive (~1% true positive) • 14% reduction in lung cancer mortality, • 521 life saved per 100K persons

  11. Testing for lung cancer? • Bronchoscopy • Biopsy • Ultrasound guided biopsy • Computer image assisted biopsy • CT guided needle biopsy • Minimally invasive surgery

  12. Prevention & early detection Prevention Prevention Prevention Early diagnosis (Screening) Early intervention

  13. Take home message • Screening data is only for asymptomatic individual • Only high risk (55-80 y, smoking 30PY) patients eligible for screening • 14% mortality benefit for screened patient • 302 LDCT required to save a life

  14. Thank You Imtiaz Ahmad, MD, FCCP Allergy Sleep & Lung Care 21st Century Oncology

  15. Back up

More Related