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This study investigates the impact of IL-1β stimulation on CCL-2 and CXCL-1 expression in naïve mice using AdLuc vector assay. The comparison of chemokine responses in the presence and absence of IL-1β highlights potential immune modulation pathways.
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B CCL-2 A CXCL-1 AdLuc AdLuc AdLuc AdLuc AdLuc AdLuc Vehicle Vehicle Vehicle Vehicle Vehicle Vehicle AdLuc AdLuc AdLuc AdLuc AdLuc AdLuc + + + + + + + + + + + + + + + + + + Naïve Naïve Naïve Naïve Naïve Naïve Vehicle Vehicle Vehicle Vehicle Vehicle Vehicle IL-1 IL-1 IL-1 IL-1 IL-1 IL-1 IL-1 IL-1 IL-1 IL-1 IL-1 IL-1 C CXCL-10 D IL-1β E CCL-3 F CCL-4