1 / 63

TVCS G ynae Cytology Workshop 12 th July 2005

TVCS G ynae Cytology Workshop 12 th July 2005. Cytology Department QEII Hospital WGC. Case 1. Age 54 Heavy discharge 2 previous inadequate smears 1. Inadequate smear. No endocervical cells or squamous metaplasia.

jalene
Télécharger la présentation

TVCS G ynae Cytology Workshop 12 th July 2005

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. TVCS Gynae CytologyWorkshop12th July 2005 Cytology Department QEII Hospital WGC

  2. Case 1 • Age 54 • Heavy discharge • 2 previous inadequate smears • 1. Inadequate smear. No endocervical cells or squamous metaplasia. • 2.Thick smear, clumps of endometrial like cells – probably related to HRT. Advise repeat mid-cycle

  3. Screener’s opinions ? degenerate endometrial cells ? ovarian Cytology report issued A poor specimen consisting mainly of superficial squamous cells. There are a few groups of degenerate endometrial like cells present not consistent with date in cycle. A gynaecological referral is advised to exclude any endometrial pathology. Case 1

  4. Case 1 outcome • Referred to another hospital • Repeat smear – negative • 3 months later • TAH & BSO • Malignant neoplasm of the ovary • moderately differentiated serous papillary cystadenocarcinoma

  5. Case2 • Age 50 • Erosion • 2 slides ; 3 months apart

  6. Case 2 outcome • Cytology report • Single and groups of malignant cells consistent with adenocarcinoma • Histology • Well differentiated early invasive papillary endocervical adenocarcinoma

  7. Case 3 • Age 54

  8. Case 3 outcome • Cytology report Malignant cells present – undifferentiated carcinoma. • Histology report of vaginal biopsy • Cellular tissue, glands and papillae from a metastatic ovarian carcinoma • Previous cystadenocarcinoma of ovary one year previously

  9. Case 4 • Age 72 • Tumour in vagina • Discharge

  10. Case 4 outcome • Additional information • Known Ca bladder • Cytology report • Malignant cells present, the morphology is consistent with a bladder primary. • Direct tumour spread from bladder to vagina

  11. Case 5 • Age 43 • POP • No periods • History of fibroids • Contact bleed • Ectropion

  12. Case 5 outcome • Cytology report • Endocervical dyskaryosis present consistent with CGIN. • Histology • High grade CGIN, few strips of squamous epithelium with CIN1 and HPV changes. • Invasion cannot be assessed as much of the dysplastic epithelium is without stromal tissue.

  13. Case 6 • Age 40 • No LMP given • Previous unsuitable smear • Ectropion

  14. Case 6 outcome • Screener comments • Vacuolated glandular groups ?endometrials • No LMP given ?significant. • Checker comments • Found on computer records that products of conception were received in histology, and this smear was taken 14 days later! • ? Are these 3D vacuolated groups due to the above. • See Pg 669 - Diagnostic Pathology - Gray &McKee • Cytology report • Unsuitable for a reliable assessment. • Numerous endometrial glandular cell groups present together with an inflammatory exudate. • Advise repeat smear

  15. Case 7 • Age 51 • Polyp in Os

  16. Case 7 outcome • Cytology report • Vacuolated malignant glandular cells present suggestive of metastasis from large intestinal carcinoma. • Histology • Caecal biopsy : moderately differentiated adenocarcinoma • 2/12 later • Cervical biopsy: lakes of mucin with 2 atypical glands, highly suspicious of mucinous adenocarcinoma

  17. Case 8 • Age 35 • TAH for CIN3 15 months previously • Ovaries left in situ • Vaginal smear

  18. Case 8 outcome • Cytology report • Numerous severely dyskaryotic squamous cells and small bizarre forms of keratinized squamous cells present. • Pattern is suspicious of invasion • Histology • (R) fornix bx – VAIN 3, evidence of invasion which has reached the margin • Vaginal wall bx – focal VAIN 3, no invasion. • Capillary proliferation and inflammation in the wall.

More Related