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DISCONTOOLS: Prioritizing Animal Health Research in the EU

DISCONTOOLS is a stakeholder-driven project focusing on disease prioritization in animal health research. The initiative aims to allocate research resources efficiently, identify critical gaps, and accelerate the development of diagnostics, vaccines, and pharmaceuticals. Through collaboration with stakeholders, the project has built consensus, established a disease database, and set a strategic research agenda for the future. Continuing work includes updating existing diseases, adding new ones, and refining the prioritization model. Stakeholders have committed funds to relaunch DISCONTOOLS, ensuring ongoing progress in advancing animal health research. Visit www.discontools.eu for more information.

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DISCONTOOLS: Prioritizing Animal Health Research in the EU

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  1. Johannes Charlier, DISCONTOOLS Project Manager 4th September, 2014 DISCONTOOLS- a method to prioritize animal health research in the E.U.

  2. Summary • DISCONTOOLS • Origin • Questions tackled • The database • Global hub for disease prioritisation in terms of research needs • Work Programme • Conclusions

  3. ETPGAH – Vision to Action Plan July 2007 August 2005 May 2006 Stakeholders, implement the StrategicResearch Agenda with the mobilisation of significanthuman and financial resources Stakeholders, define a StrategicResearch Agenda setting the necessary mid- to longterm objectives Stakeholders, led by industry, come together to agree on a common vision for the technology

  4. Framework Programme 7 Coordination of Funding April 2008 - 45 months €997,218 Feb 2011 - 48 months €999,130 Jan 2012 - 48 months €2m

  5. Background • DISCONTOOLS was a Stakeholder driven project • All European & Global Stakeholders welcomed to join • 5 Year Project - March, 2008 to February, 2013 • Output • Disease database – 52 diseases • Gap analysis for each disease • Prioritisation model on public website • Methodology to identify & deploy new research technologies in the animal health research world

  6. Questions Tackled • How do we decide where to spend scarce research resources? • Which diseases? • Which gap(s) in each disease? • Priority of whom? • Research community? • Funders of research? • People at coal face – CVO, Vet, Farmer? • Industry?

  7. www.discontools.eu

  8. The disease database

  9. View disease info – control tools

  10. Disease scoring criteria

  11. Gap analysis – Diagnostics, vaccines, pharmaceuticals

  12. Sample report – all diseases ranked by score

  13. Prioritisation of Epizootic diseases

  14. Prioritisation of Zoonotic diseases

  15. Prioritisation of Food producing diseases

  16. Achievements & Economics • DISCONTOOLS finished on February 28th, 2013 • Built consensus across stakeholders • Focus on critical gaps • Agreement on need to continue • Make best use of €400m from public sector & €400m from private sector • Hasten the arrival of new diagnostics, vaccines & pharmaceuticals • Disease burden of 20% on animal production valued at €141b (in EU) – reduce cost by €28b!

  17. Continuing DISCONTOOLS Work! • Business case made – need € 100,000 per year • Need 14 countries to fund at € 7000 each • 10 countries/funders have committed to date - others considering • Held meeting of funders in February, 2014 • Sufficient funds to re-launch DISCONTOOLS!

  18. DISCONTOOLS Work in 2014 • Commenced DISCONTOOLS work in June, 2014 • Update existing diseases over time • Add new diseases • Refine & further develop model

  19. 12 diseases in focus - 2014 • Existing - AI, ASF, BT, Campylobacter, Cysticercosis, E. coli, FMD, Nematodes, ParaTB, PRRS, SIV • New – PEDV • List determined by funders with offer to work on Cysticercosis & PEDV

  20. Logistics • Expert Groups formed or being formed ideally including: • laboratory expertise, an epidemiologist, an industry representative, a diagnostics expert and an individual with economic/trade expertise • Documents to be updated: • Disease & Product analysis • Gap Analysis • Prioritisation • 2 page summary

  21. Conclusions - 1 • Public website with searchable database • Stakeholder agreed prioritised research gaps • Research agenda for the future has been established! • Focus funding on prioritised research gaps • ANIHWA, Horizon 2020, Countries, Industry, Trusts, Foundations, Charities, etc.

  22. Conclusions - 2 • The work of DISCONTOOLS will continue & evolve driven especially by funders to meet their needs • We should organise the deployment of € 800 million (3 billion globally) in the best way possible! • The prize of hastening the development of new or better disease control tools is enormous - €28 billion per year in the EU alone! • We should make DISCONTOOLS our global hub where we pool our resources

  23. Rue Defacqz, 1 • 1000 Brussels, Belgium • Tel.: +32 (0)2 543 7570 • Fax: +32 (0)2 537 0049 For more information please consult: www.discontools.eu

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