TOXICOLOGY
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TOXICOLOGY. DRUGS. DRUGS. NATURAL OR SYNTHETIC SUBSTANCES USED TO PRODUCE PSYCHOLOGICAL OR PHYSIOLOGICAL EFFECTS. Psychological dependence. Psychological Dependence. Drug is used to fulfill EMOTIONAL needs Cope with life
TOXICOLOGY
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TOXICOLOGY DRUGS
DRUGS • NATURAL OR SYNTHETIC SUBSTANCES • USED TO PRODUCE PSYCHOLOGICAL OR PHYSIOLOGICAL EFFECTS
Psychological Dependence Drug is used to fulfill EMOTIONAL needs • Cope with life • To feel more comfortable in social settings CRACK is the most PSYCHOLOGICALLY addictive
Physical Dependence • Physical dependence means the body gets used to the drug, it needs more and more of it to accomplish the same effect. • Finally, the drug is merely used to counteract the withdrawal symptoms that appear when no drugs are being taken. Perspiring, feeling cold, goose flesh/pimples (cold turkey), running nose, stomach cramps, aching muscles, diarrhea.
DRUGS • NECESSARY TO SUSTAIN AND PROLONG LIFE EXAMPLES: • INSULIN • AIDS DRUGS
DRUGS • AS AN ESCAPE
DRUGS AS A WAY TO END LIFE LEGAL EUTHANASIA: IN US - OREGON NETHERLANDS, BELGIUM SWITZERLAND
Narcotics Substances that reduce or relieve pain and induce sleep
Heroin Derived from morphine which is obtained from the opium poppy
Street Names: “dope” “smack” “China white” “Cheese” “Black Tar”
How used: • Mainlining: injecting into a vein or muscle • Smoked (mixed with marijuana in a joint) • Snorted as a powder
Short-term Effects SLOWS DOWN
Long-Term Effects Most physically Addictive drug
Chronic use Heart Infections liver disease Heroin tolerance
CODEINE • Prepared synthetically from MORPHINE • 1/6 as strong as morphine
Methadone synthetic opiate Used to treat heroin addiction
Propoxyphene (Darvon) Pain Reliever 1 of top 10 drugs found in bodies at autopsy
Oxycontin • acetaminophen (tylenol) • and oxycodone • used to treat severe pain • tablets crushed & ingested • or dissolved in water and • injected
SHORT-TERM EFFECTS OF OXYCONTIN • “RUSH” SIMILAR TO HEROIN • RESPIRATORY DEPRESSION • CONSTIPATION, NAUSEA, VOMITING • CARDIAC ARREST • SEVERE WITHDRAWAL (“FLU x 1000”- 2WKS)
Barbiturates Relax and produce sleep
“Barbs” “Yellow Jackets”“Blue Devils” “Reds” Fast-acting barbiturates are the most commonly abused : Secobarbital, Pentobarbital, Amobarbital
1/3 of all Drug-related deaths
Short-term Effects • Relaxes • Impairment of higher thinking • Induces sleep
Long-term Effects of Barbiturates Withdrawal: • Insomnia • Muscle spasms • Delirium • Convulsions • Can lead to death
Methaqualone • Quaaludes “Ludes” • Non-barbiturate depressant • Powerful sedative & muscle relaxant
Tranquilizers • Depressants that relax • Proper dosage does not impair
Ketamine • Veterinarian anesthesia • “Special K” “Vitamin K” new ecstasy
Ketamine Mixed in drinks As a powder–snorted Hallucinogenatory effects: -Euphoria -Delirium -Amnesia -High blood pressure Higher doses can stop breathing-DEATH
“K-HOLE” • NO PAIN • HALLUCINOGEN • COMA
GHB “Liquid X” “Liquid E” “G”
GHB IS MADE OF: A CNS DEPRESSANT
GHB: DATE-RAPE DRUG • COLORLESS • ODORLESS • SLIGHT, BITTER TASTE • DISSOLVES IN WATER
GHB: Short-term Effects • Drowsiness • Vomiting • Delusions • Depression • Amnesia • Coma • Death Increasing dosages
GHB: Long-term Effects • Physically addictive • unknown
“Roofies” Tasteless Odorless Dissolves in water Used crushed Also Legal in 60 countries ….not in U.S.
Rohypnol: Short-term Effects Sedative Hypnotic effect Muscle relaxant Amnesia At higher dosages: respiratory depression With alcohol: no memory COMA
HUFFING: INHALANT ABUSE • RAG IS SOAKED IN INHALANT AND PLACED IN MOUTH. THE INHALANT VAPORIZES AND GOES TO THE LUNGS,THEN TO THE BRAIN • COMMON HOUSEHOLD PRODUCTS • ONLY TYPE OF DRUG ABUSE MORE COMMON IN YOUNGER CHILDREN THAN IN TEENS
GLUE-SNIFFING USUALLY TOLUENE SHORT-TERM EFFECTS: Exhilaration, euphoria,slurred Speech, impaired judgement, Double vision LONG-TERM EFFECTS: Liver, heart, brain damage DEATH
LEGALSTIMULANTS SPEEDS UP CNS
AMPHETAMINES • SYNTHETIC STIMULANTS • “UPPERS” • “SPEED”
THE NAZIS USED AMPHETAMINES SO TROOPS WOULD NOT NEED SLEEP WORLD WAR II SOLDIERS USED AMPHETAMINES TO STAY AWAKE
METHAMPHETAMINES “ICE” “CRANK” “METH” “SPEED”
METHAMPHETAMINES • Powerful stimulant • Taken orally, injected, snorted, or smoked • Use is on rise because it is mixed with Ecstacy
Meth: Short-term Effects Increased energy Decrease in appetite Euphoria Irritability Aggression Then EXHAUSTION and DEPRESSION Decrease in Heart and Breathing Rates