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Cyclin D3

IL-2/15R b. IL-2R a. g c. A. C-myc. Syk. 1. SOCS1 SOCS3. Bcl-2. s. JAK1 / (JAK3). C. JAK3. V. STAT. Bcl-2. Proliferation. Y. 338. Eos. 1. 2. V. LNK-Grb-2-SOS. 2. a. 355 358 361. Ras-Raf-MAPK. PI 3-K. c-fos. Bad. Akt. E2F. IRS-1/ Cbl /CrkL. Y. 392. Nmi.

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Cyclin D3

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  1. IL-2/15Rb IL-2Ra gc A C-myc Syk 1 SOCS1 SOCS3 Bcl-2 s JAK1/(JAK3) C JAK3 V STAT Bcl-2 Proliferation Y 338 Eos 1 2 V LNK-Grb-2-SOS 2 a 355 358 361 Ras-Raf-MAPK PI 3-K c-fos Bad Akt E2F IRS-1/Cbl/CrkL Y 392 Nmi Cyclins Bcl-Xi Apoptosis h IRF STAT-5A/B STAT-3 FasL/Fas PCNA Y 510 Shp SOCS1 SOCS3 IRF-1 IL-2Ra CISH perforin rIL-2 B No-Stim PBMC Pre-Sort PBMC Pre-Sort DUSP5 STAT-3 STAT-5a Cyclin D3 SOS STAT-1 FAS JAK3 PI 3-K E2F

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